Question from NMRWiki Q&A forum Long-range 1H-{15N} coupling (HMBC)

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[Question from NMRWiki Q&A forum] Long-range 1H-{15N} coupling (HMBC)

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10-29-2012, 07:03 PM

nmrlearner

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Long-range 1H-{15N} coupling (HMBC)

Long-range 1H-{15N} coupling (HMBC)

Hello All

I have two examples of what appears to be 6J coupling between 1H and 15N using gradient HMBC experiments with 15N at natural abundance. For such an experiment, 2J and 3J correlations are typical, sometimes 4J (W-type) but I've never seen 6J before.

Has anyone else ever seen correlations over this distance? Any other comments?

Craig.

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