1,3-Bis(diphenylene)-2-phenylallyl (BDPA) radicals are promising polarizing agents for increasing the sensitivity of NMR spectroscopy through dynamic nuclear polarization (DNP), but have low persistence and solubility in aqueous media. New tetraalkyl/aryl-ammonium derivatives of BDPA are soluble in polar solvents and are highly persistent, with 5–20-fold lower initial rates of degradation than BDPA.
Heteronuclear DNP of 1H and 19F nuclei using BDPA as a polarizing agent #DNPNMR
From The DNP-NMR Blog:
Heteronuclear DNP of 1H and 19F nuclei using BDPA as a polarizing agent #DNPNMR
Gennaro, Antonio, Alexander Karabanov, Alexey Potapov, and Walter Köckenberger. “Heteronuclear DNP of 1H and 19F Nuclei Using BDPA as a Polarizing Agent.” Physical Chemistry Chemical Physics 22, no. 15 (2020): 7803–16.
https://doi.org/10.1039/D0CP00892C.
This work explores the dynamic nuclear polarization (DNP) of 1H and 19F nuclei in a sample of 25/75 (% v/v) fluorobenzene/toluene containing the radical 1,3-bisphenylene-2-phenylallyl radical (BDPA) as a polarizing agent....
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08-07-2020 08:10 PM
Hyperpolarized water through dissolution dynamic nuclear polarization with UV-generated radicals #DNPNMR
From The DNP-NMR Blog:
Hyperpolarized water through dissolution dynamic nuclear polarization with UV-generated radicals #DNPNMR
Pinon, Arthur C., Andrea Capozzi, and Jan Henrik Ardenkjær-Larsen. “Hyperpolarized Water through Dissolution Dynamic Nuclear Polarization with UV-Generated Radicals.” Communications Chemistry 3, no. 1 (December 2020): 57.
https://doi.org/10.1038/s42004-020-0301-6.
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08-07-2020 08:10 PM
TinyPols: a family of water-soluble binitroxides tailored for dynamic nuclear polarization enhanced NMR spectroscopy at 18.8 and 21.1 T #DNPNMR
From The DNP-NMR Blog:
TinyPols: a family of water-soluble binitroxides tailored for dynamic nuclear polarization enhanced NMR spectroscopy at 18.8 and 21.1 T #DNPNMR
Lund, Alicia, Gilles Casano, Georges Menzildjian, Monu Kaushik, Gabriele Stevanato, Maxim Yulikov, Ribal Jabbour, et al. “TinyPols: A Family of Water-Soluble Binitroxides Tailored for Dynamic Nuclear Polarization Enhanced NMR Spectroscopy at 18.8 and 21.1 T.” Chemical Science 11, no. 10 (2020): 2810–18.
https://doi.org/10.1039/C9SC05384K.
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06-25-2020 02:58 AM
Efficiency of Water-Soluble Nitroxide Biradicals for Dynamic Nuclear Polarization in Rotating Solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as New Polarizing Agents #DNPNMR
From The DNP-NMR Blog:
Efficiency of Water-Soluble Nitroxide Biradicals for Dynamic Nuclear Polarization in Rotating Solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as New Polarizing Agents #DNPNMR
Geiger, Michel-Andreas, Anil P. Jagtap, Monu Kaushik, Han Sun, Daniel Stöppler, Snorri T. Sigurdsson, Björn Corzilius, and Hartmut Oschkinat. “Efficiency of Water-Soluble Nitroxide Biradicals for Dynamic Nuclear Polarization in Rotating Solids at 9.4 T: BcTol-M and Cyolyl-TOTAPOL as New Polarizing Agents.” Chemistry - A European Journal 24, no. 51 (September 12, 2018): 13485–94.
...
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11-25-2018 06:02 AM
Dissolution DNP using trityl radicals at 7 T field #DNPNMR
From The DNP-NMR Blog:
Dissolution DNP using trityl radicals at 7 T field #DNPNMR
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Jahnig, F., et al., Dissolution DNP using trityl radicals at 7 T field. Phys. Chem. Chem. Phys., 2017. 19(29): p. 19196-19204.
https://www.ncbi.nlm.nih.gov/pubmed/28702550
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11-24-2017 05:56 PM
[NMR paper] NMR structure of the water soluble A?17-34 peptide.
NMR structure of the water soluble A?17-34 peptide.
Related Articles NMR structure of the water soluble A?17-34 peptide.
Biosci Rep. 2014 Oct 6;
Authors: Fonar G, Samson AO
Abstract
Alzheimer's disease is the most common neurodegenerative disorder in the world. Its most significant symptoms are memory loss and decrease in cognition. Alzheimer's disease is characterized by aggregation of two proteins in the brain namely amyloid ? (A?) and tau. Recent evidence suggests that the interaction of soluble A? with nicotinic...
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10-07-2014 02:31 PM
Rationalizing Overhauser DNP of nitroxide radicals in water through MD simulations
From The DNP-NMR Blog:
Rationalizing Overhauser DNP of nitroxide radicals in water through MD simulations
Sezer, D., Rationalizing Overhauser DNP of nitroxide radicals in water through MD simulations. Phys Chem Chem Phys, 2014. 16(3): p. 1022-32.
http://www.ncbi.nlm.nih.gov/pubmed/24284869
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01-31-2014 06:44 PM
[NMR paper] Interaction of the water-soluble protein aprotinin with liposomes: gel-filtration, tu
Interaction of the water-soluble protein aprotinin with liposomes: gel-filtration, turbidity studies, and 31P NMR studies.
Related Articles Interaction of the water-soluble protein aprotinin with liposomes: gel-filtration, turbidity studies, and 31P NMR studies.
J Liposome Res. 2003 Nov;13(3-4):213-29
Authors: Tiourina O, Sharf T, Balkina A, Ollivon M, Selischeva A, Sorokoumova G, Larionova N
The interactions of a water-soluble nonmembrane protein aprotinin with multilamellar vesicles (MLV) and small unilamellar vesicles (SUV) from soybean...
Water-soluble BDPA radicals with improved persistence #DNPNMR
Linear Mode
