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This article describes an elegant way to increase the throughput of a hyperpolarizer by storing the hyperpolarized materials separated from the polarizing agents.
Ji, X., et al., Transportable hyperpolarized metabolites. Nat Commun, 2017. 8: p. 13975.
<div style="text-align: justify;">Nuclear spin hyperpolarization of 13C-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by MRI. However, because of the short lifetime of the hyperpolarized magnetization (typically
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Thermal annihilation of photo-induced radicals following dynamic nuclear polarization to produce transportable frozen hyperpolarized 13C-substrates
From The DNP-NMR Blog:
Thermal annihilation of photo-induced radicals following dynamic nuclear polarization to produce transportable frozen hyperpolarized 13C-substrates
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Capozzi, A., et al., Thermal annihilation of photo-induced radicals following dynamic nuclear polarization to produce transportable frozen hyperpolarized 13C-substrates. 2017. 8: p. 15757.
http://dx.doi.org/10.1038/ncomms15757
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[NMR paper] Quantification of metabolites by NMR spectroscopy in the presence of protein.
Quantification of metabolites by NMR spectroscopy in the presence of protein.
Related Articles Quantification of metabolites by NMR spectroscopy in the presence of protein.
J Proteome Res. 2017 Mar 15;:
Authors: Wallmeier J, Samol C, Ellmann L, Zacharias HU, Vogl FC, Garcia M, Dettmer K, Oefner PJ, Gronwald W
Abstract
The high reliability of NMR spectroscopy makes it an ideal tool for large-scale metabolomic studies. However, the complexity of biofluids and, in particular, the presence of macromolecules poses a significant...
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Hyperpolarized Nanodiamond Surfaces #DNPNMR
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Rej, E., et al., Hyperpolarized Nanodiamond Surfaces. J Am Chem Soc, 2017. 139(1): p. 193-199.
https://www.ncbi.nlm.nih.gov/pubmed/28009158
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From The DNP-NMR Blog:
Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins
Vuichoud, B., et al., Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins. Chemistry, 2016: p. n/a-n/a.
https://www.ncbi.nlm.nih.gov/pubmed/27546550
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Constant-variable flip angles for hyperpolarized media MRI #DNPNMR
From The DNP-NMR Blog:
Constant-variable flip angles for hyperpolarized media MRI #DNPNMR
Deng, H., et al., Constant-variable flip angles for hyperpolarized media MRI. J. Magn. Reson., 2016. 263: p. 92-100.
http://www.sciencedirect.com/science/article/pii/S1090780716000203
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In vivo single-shot 13C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding
From The DNP-NMR Blog:
In vivo single-shot 13C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding
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http://www.ncbi.nlm.nih.gov/pubmed/24486720
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From The DNP-NMR Blog:
In vivo single-shot C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding
Schmidt, R., et al., In vivo single-shot C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding. J Magn Reson, 2014. 240C(0): p. 8-15.
http://www.ncbi.nlm.nih.gov/pubmed/24486720
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(1)H NMR study of monocrotaline and its metabolites in human blood.
(1)H NMR study of monocrotaline and its metabolites in human blood.
(1)H NMR study of monocrotaline and its metabolites in human blood.
Food Chem Toxicol. 2011 Aug 6;
Authors: Yang YC, Crowder J, Wardle NJ, Yang L, White KN, Wang ZT, Annie Bligh SW
Monocrotaline (MCT) is a naturally occurring hepatotoxic pyrrolizidine alkaloid found in plants. This investigation is aimed at furthering the understanding of the role of blood in mediating the transport of MCT and its reactive metabolites in humans. Reactions of monocrotaline and its metabolites,...
Transportable hyperpolarized metabolites #DNPNMR
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