Dynamic nuclear polarization (DNP), a means of transferring spin polarization from electrons to nuclei, can enhance the nuclear spin polarization (hence the NMR sensitivity) in bulk materials at most 660 times for 1H spins, using electron spins in thermal equilibrium as polarizing agents. By using electron spins in photo-excited triplet states instead, DNP can overcome the above limit. We demonstrate a 1H spin polarization of 34%, which gives an enhancement factor of 250,000 in 0.40 T, while maintaining a bulk sample (~0.6 mg, ~0.7 × 0.7 × 1 mm3) containing >1019 1H spins at room temperature. Room temperature hyperpolarization achieved with DNP using photo-excited triplet electrons has potentials to be applied to a wide range of fields, including NMR spectroscopy and MRI as well as fundamental physics.
[NMR paper] Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Related Articles Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E445-54
Authors: Fenwick RB, van den Bedem H, Fraser JS, Wright PE
Abstract
Detailed descriptions of atomic coordinates and motions are required for an understanding of protein dynamics and their relation to molecular recognition, catalytic function, and allostery. Historically, NMR...
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01-30-2014 05:38 PM
Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control
From The DNP-NMR Blog:
Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control
Sakaguchi, S., et al., Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2013. 317(0): p. 679-684.
http://www.sciencedirect.com/science/article/pii/S0168583X13008872
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01-23-2014 01:37 AM
Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control
From The DNP-NMR Blog:
Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control
Sakaguchi, S., et al., Proton polarization in photo-excited aromatic molecule at room temperature enhanced by intense optical source and temperature control. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2013(0).
http://www.sciencedirect.com/science/article/pii/S0168583X13008872
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11-21-2013 01:14 AM
Dynamic Nuclear Hyperpolarization in Liquids
From The DNP-NMR Blog:
Dynamic Nuclear Hyperpolarization in Liquids
Günther, U., Dynamic Nuclear Hyperpolarization in Liquids, in Modern NMR Methodology, H. Heise and S. Matthews, Editors. 2013, Springer Berlin Heidelberg. p. 23-69.
http://dx.doi.org/10.1007/128_2011_229
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07-18-2013 12:39 AM
[Question from NMRWiki Q&A forum] bulk water relaxation dependence on temperature
bulk water relaxation dependence on temperature
Is liquid water's relaxation rate strongly dependent on temperature, and does anyone have a link to a good online article with the dependency equation?Thanks!
Check if somebody has answered this question on NMRWiki QA forum
[NMR paper] Improving NMR sensitivity in room temperature and cooled probes with dipolar ions.
Improving NMR sensitivity in room temperature and cooled probes with dipolar ions.
Related Articles Improving NMR sensitivity in room temperature and cooled probes with dipolar ions.
J Magn Reson. 2005 Apr;173(2):339-43
Authors: Lane AN, Arumugam S
The response of inverse triple resonance cold and conventional probes to ionic strength has been compared under a variety of conditions relevant to protein NMR. Increasing the salt concentration degrades probe performance in terms of sensitivity, and the effect is more severe for cold probes and...
Room temperature hyperpolarization of nuclear spins in bulk
Linear Mode
