Reality #1: LC/MS has become the primary analytical check for the medicinal chemist. I Love NMR, but it's the reality Reality #2: More often than not, NMR spectra are merely glanced at: Sometimes interpretation is based on the presence or...
[NMR paper] Anomalous diffusion in a gel-fluid lipid environment: a combined solid-state NMR and
Anomalous diffusion in a gel-fluid lipid environment: a combined solid-state NMR and obstructed random-walk perspective.
Related Articles Anomalous diffusion in a gel-fluid lipid environment: a combined solid-state NMR and obstructed random-walk perspective.
Biophys J. 2004 Oct;87(4):2456-69
Authors: Arnold A, Paris M, Auger M
Lateral diffusion is an essential process for the functioning of biological membranes. Solid-state nuclear magnetic resonance (NMR) is, a priori, a well-suited technique to study lateral diffusion within a heterogeneous...
nmrlearner
Journal club
0
11-24-2010 10:01 PM
[NMR paper] Proton NMR study of the heme environment in bacterial quinol oxidases.
Proton NMR study of the heme environment in bacterial quinol oxidases.
Related Articles Proton NMR study of the heme environment in bacterial quinol oxidases.
Arch Biochem Biophys. 2004 Jan 15;421(2):186-91
Authors: Zhang J, Osborne JP, Gennis RB, Wang X
The heme environment and ligand binding properties of two relatively large membrane proteins containing multiple paramagnetic metal centers, cytochrome bo3 and bd quinol oxidases, have been studied by high field proton nuclear magnetic resonance (NMR) spectroscopy. The oxidized bo3 enzyme...
nmrlearner
Journal club
0
11-24-2010 09:25 PM
[NMR paper] Structure of gramicidin a in a lipid bilayer environment determined using molecular d
Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data.
Related Articles Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data.
J Am Chem Soc. 2003 Aug 13;125(32):9868-77
Authors: Allen TW, Andersen OS, Roux B
Two different high-resolution structures recently have been proposed for the membrane-spanning gramicidin A channel: one based on solid-state NMR experiments in oriented phospholipid...
nmrlearner
Journal club
0
11-24-2010 09:16 PM
[NMR paper] Exploration of the structural environment of the iron-sulfur cluster in putidaredoxin
Exploration of the structural environment of the iron-sulfur cluster in putidaredoxin by nitrogen-15 NMR spectroscopy of selectively labeled cysteine residues.
Related Articles Exploration of the structural environment of the iron-sulfur cluster in putidaredoxin by nitrogen-15 NMR spectroscopy of selectively labeled cysteine residues.
Biochem Biophys Res Commun. 1998 Aug 28;249(3):773-80
Authors: Sari N, Holden MJ, Mayhew MP, Vilker VL, Coxon B
Putidaredoxin is a di-iron protein whose paramagnetic region is not well characterized by 1H...
nmrlearner
Journal club
0
11-17-2010 11:15 PM
[NMR paper] Proton NMR investigation of the [4Fe--4S]1+ cluster environment of nitrogenase iron p
Proton NMR investigation of the 1+ cluster environment of nitrogenase iron protein from Azotobacter vinelandii: defining nucleotide-induced conformational changes.
Related Articles Proton NMR investigation of the 1+ cluster environment of nitrogenase iron protein from Azotobacter vinelandii: defining nucleotide-induced conformational changes.
Biochemistry. 1995 Dec 5;34(48):15646-53
Authors: Lanzilotta WN, Holz RC, Seefeldt LC
This work presents the complete assignment of the isotropically shifted 1H NMR resonances of Azotobacter vinelandii...
nmrlearner
Journal club
0
08-22-2010 03:50 AM
[NMR paper] 1H NMR investigation of the paramagnetic cluster environment in Pyrococcus furiosus t
1H NMR investigation of the paramagnetic cluster environment in Pyrococcus furiosus three-iron ferredoxin: sequence-specific assignment of ligated cysteines independent of tertiary structure.
Related Articles 1H NMR investigation of the paramagnetic cluster environment in Pyrococcus furiosus three-iron ferredoxin: sequence-specific assignment of ligated cysteines independent of tertiary structure.
Biochemistry. 1995 Jan 17;34(2):600-10
Authors: Gorst CM, Yeh YH, Teng Q, Calzolai L, Zhou ZH, Adams MW, La Mar GN
One- and two-dimensional 1H NMR...
nmrlearner
Journal club
0
08-22-2010 03:41 AM
[NMR paper] Characterization of the haem environment in Methylophilus methylotrophus ferricytochr
Characterization of the haem environment in Methylophilus methylotrophus ferricytochrome c" by 1H-NMR.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles Characterization of the haem environment in Methylophilus methylotrophus ferricytochrome c" by 1H-NMR.
Eur J Biochem. 1993 Aug 1;215(3):817-24
Authors: Costa HS, Santos H, Turner DL
Two-dimensional NMR techniques have been used to assign proton resonances in the haem cavity of...
nmrlearner
Journal club
0
08-22-2010 03:01 AM
[NMR paper] NMR studies of the structure and environment of the milk protein alpha-lactalbumin.
NMR studies of the structure and environment of the milk protein alpha-lactalbumin.
Related Articles NMR studies of the structure and environment of the milk protein alpha-lactalbumin.
Basic Life Sci. 1990;56:231-53
Authors: Berliner LJ, Kaptein R, Koga K, Musci G
The Realities of NMR in the New(ish) Discovery Environment
Linear Mode
