Dynamic nuclear polarization (DNP) under magic-angle spinning (MAS) is transforming the scope of solid-state NMR by enormous signal amplification through transfer of polarization from electron spins to nuclear spins. Contemporary MAS-DNP exclusively relies on monochromatic continuous-wave (CW) irradiation of the electron spin resonance. This limits control on electron spin dynamics, which renders the DNP process inefficient, especially at higher magnetic fields and non cryogenic temperatures. Pulse-shaped microwave irradiation of the electron spins is predicted to overcome these challenges but hitherto has never been implemented under MAS. Here, we debut pulse-shaped microwave irradiation using arbitrary-waveform generation (AWG) which allows controlled recruitment of a greater number of electron spins per unit time, favorable for MAS-DNP. Experiments and quantum mechanical simulations demonstrate that pulse-shaped DNP is superior to CW-DNP for mixed radical system, especially when the electron spin resonance is heterogeneously broadened and/or when its spin-lattice relaxation is fast compared to the MAS rotor period, opening new prospects for MAS-DNP.
De novo prediction of cross-effect efficiency for magic angle spinning dynamic nuclear polarization #DNPNMR
From The DNP-NMR Blog:
De novo prediction of cross-effect efficiency for magic angle spinning dynamic nuclear polarization #DNPNMR
Mentink-Vigier, Frédéric, Anne-Laure Barra, Johan van Tol, Sabine Hediger, Daniel Lee, and Gaël De Paëpe. “De Novo Prediction of Cross-Effect Efficiency for Magic Angle Spinning Dynamic Nuclear Polarization.” Physical Chemistry Chemical Physics 21, no. 4 (2019): 2166–76.
https://doi.org/10.1039/C8CP06819D.
Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning #DNPNMR
From The DNP-NMR Blog:
Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning #DNPNMR
Jaudzems, Kristaps, Andrea Bertarello, Sachin R. Chaudhari, Andrea Pica, Diane Cala-De Paepe, Emeline Barbet-Massin, Andrew J. Pell, et al. “Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning.” Angewandte Chemie 0 (2018).
https://doi.org/10.1002/ange.201801016.
Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90L of liquid nitrogen per day #DNPNMR
From The DNP-NMR Blog:
Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90L of liquid nitrogen per day #DNPNMR
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Albert, B.J., et al., Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90L of liquid nitrogen per day. J. Magn. Reson., 2017. 283(Supplement C): p. 71-78.
https://doi.org/10.1016/j.jmr.2017.08.014
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12-20-2017 10:12 PM
Dynamic nuclear polarization at 40 kHz magic angle spinning #DNPNMR
From The DNP-NMR Blog:
Dynamic nuclear polarization at 40 kHz magic angle spinning #DNPNMR
Chaudhari, S.R., et al., Dynamic nuclear polarization at 40 kHz magic angle spinning. Phys Chem Chem Phys, 2016. 18(15): p. 10616-22.
http://www.ncbi.nlm.nih.gov/pubmed/27035630
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08-23-2016 01:02 AM
Instrumentation for solid-state dynamic nuclear polarization with magic angle spinning NMR
From The DNP-NMR Blog:
Instrumentation for solid-state dynamic nuclear polarization with magic angle spinning NMR
Rosay, M., M. Blank, and F. Engelke, Instrumentation for solid-state dynamic nuclear polarization with magic angle spinning NMR. J Magn Reson, 2016. 264: p. 88-98.
http://www.ncbi.nlm.nih.gov/pubmed/26920834
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04-18-2016 03:17 PM
Theoretical Aspects of Magic Angle Spinning - Dynamic Nuclear Polarization
From The DNP-NMR Blog:
Theoretical Aspects of Magic Angle Spinning - Dynamic Nuclear Polarization
Mentink-Vigier, F., et al., Theoretical Aspects of Magic Angle Spinning - Dynamic Nuclear Polarization. J. Magn. Reson., 2015.
http://www.sciencedirect.com/science/article/pii/S1090780715001500
Pulse-Shaped Dynamic Nuclear Polarization under Magic-Angle Spinning #DNPNMR
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