Lilburn, D.M.L., G.E. Pavlovskaya, and T. Meersmann, Perspectives of hyperpolarized noble gas MRI beyond 3He. J. Magn. Reson., 2013. 229(0): p. 173-186.
Nuclear Magnetic Resonance (NMR) studies with hyperpolarized (hp) noble gases are at an exciting interface between physics, chemistry, materials science and biomedical sciences. This paper intends to provide a brief overview and outlook of magnetic resonance imaging (MRI) with hp noble gases other than hp 3He. A particular focus are the many intriguing experiments with 129Xe, some of which have already matured to useful MRI protocols, while others display high potential for future MRI applications. Quite naturally for MRI applications the major usage so far has been for biomedical research but perspectives for engineering and materials science studies are also provided. In addition, the prospects for surface sensitive contrast with hp 83Kr MRI is discussed.
[NMR paper] NMR spectroscopic study of noble gas binding into the engineered cavity of HPr(I14A) from Staphylococcus carnosus.
NMR spectroscopic study of noble gas binding into the engineered cavity of HPr(I14A) from Staphylococcus carnosus.
Related Articles NMR spectroscopic study of noble gas binding into the engineered cavity of HPr(I14A) from Staphylococcus carnosus.
J Phys Chem B. 2005 Sep 29;109(38):17795-8
Authors: Nisius L, Stadler M, Kalbitzer HR, Brunner E
Xenon binding into preexisting cavities in proteins is a well-known phenomenon. Here we investigate the interaction of helium, neon, and argon with hydrophobic cavities in proteins by NMR spectroscopy. 1H...
nmrlearner
Journal club
0
12-01-2010 06:56 PM
[BMNRC community] Perspectives on NMR in drug discovery: a technique comes of age
Perspectives on NMR in drug discovery: a technique comes of age
http://www.nature.com/nrd/journal/v7/n9/abs/nrd2606.html
Nature Reviews Drug Discovery 7, 738-745 (September 2008) | doi:10.1038/nrd2606
Go to BMNRC community to find more info about this topic.