Optically generated hyperpolarization for sensitivity enhancement in solution-state NMR spectroscopy #DNPNMR

		BioNMR > NMR community > News from NMR blogs
Optically generated hyperpolarization for sensitivity enhancement in solution-state NMR spectroscopy #DNPNMR

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

02-29-2020, 09:52 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Optically generated hyperpolarization for sensitivity enhancement in solution-state NMR spectroscopy #DNPNMR

From The DNP-NMR Blog:

Optically generated hyperpolarization for sensitivity enhancement in solution-state NMR spectroscopy #DNPNMR

Dale, Matthew W., and Christopher J. Wedge. “Optically Generated Hyperpolarization for Sensitivity Enhancement in Solution-State NMR Spectroscopy.” Chemical Communications 52, no. 90 (2016): 13221–24.

https://doi.org/10.1039/C6CC06651H.

We show that optical excitation of radical triplet pair systems can produce a fourfold NMR signal enhancement in solution, without the need for microwave pumping. Development of optical hyperpolarization methods will significantly impact all NMR user groups by boosting sensitivity and reducing signal averaging times.

Go to The DNP-NMR Blog for more info.

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Sensitivity-Enhanced 207 Pb Solid-State NMR Spectroscopy for the Rapid, Non-Destructive Characterization of Organolead Halide Perovskites #DNPNMR From The DNP-NMR Blog: Sensitivity-Enhanced 207 Pb Solid-State NMR Spectroscopy for the Rapid, Non-Destructive Characterization of Organolead Halide Perovskites #DNPNMR Hanrahan, Michael P., Long Men, Bryan A. Rosales, Javier Vela, and Aaron J. Rossini. “Sensitivity-Enhanced 207 Pb Solid-State NMR Spectroscopy for the Rapid, Non-Destructive Characterization of Organolead Halide Perovskites.” Chemistry of Materials, October 4, 2018. https://doi.org/10.1021/acs.chemmater.8b01899.	nmrlearner	News from NMR blogs	0	11-25-2018 06:02 AM
Improving Sensitivity of Solid-state NMR Spectroscopy by Rational Design of Polarizing Agents for Dynamic Nuclear Polarization #DNPNMR From The DNP-NMR Blog: Improving Sensitivity of Solid-state NMR Spectroscopy by Rational Design of Polarizing Agents for Dynamic Nuclear Polarization #DNPNMR Kubicki, D.J. and L. Emsley, Improving Sensitivity of Solid-state NMR Spectroscopy by Rational Design of Polarizing Agents for Dynamic Nuclear Polarization. Chimia (Aarau), 2017. 71(4): p. 190-194. https://www.ncbi.nlm.nih.gov/pubmed/28446334	nmrlearner	News from NMR blogs	0	05-21-2018 06:16 PM
Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR #DNPNMR From The DNP-NMR Blog: Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR #DNPNMR p.p1 {margin: 0.0px 0.0px 0.0px 36.0px; text-indent: -36.0px; font: 12.0px Helvetica} Lilly Thankamony, A.S., et al., Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR. Prog Nucl Magn Reson Spectrosc, 2017. 102-103(Supplement C): p. 120-195. https://www.ncbi.nlm.nih.gov/pubmed/29157490	nmrlearner	News from NMR blogs	0	11-30-2017 01:10 AM
Unprecedented Carbon Signal Enhancement in Liquid-State NMR Spectroscopy #DNPNMR From The DNP-NMR Blog: Unprecedented Carbon Signal Enhancement in Liquid-State NMR Spectroscopy #DNPNMR p.p1 {margin: 0.0px 0.0px 0.0px 36.0px; text-indent: -36.0px; font: 12.0px Helvetica} Pinter, G. and H. Schwalbe, Unprecedented Carbon Signal Enhancement in Liquid-State NMR Spectroscopy. Angew Chem Int Ed Engl, 2017. 56(29): p. 8332-8334. https://www.ncbi.nlm.nih.gov/pubmed/28544115	nmrlearner	News from NMR blogs	0	09-19-2017 04:02 AM
Sensitivity enhancement in solution NMR: emerging ideas and new frontiers From The DNP-NMR Blog: Sensitivity enhancement in solution NMR: emerging ideas and new frontiers Lee, J.H., Y. Okuno, and S. Cavagnero, Sensitivity enhancement in solution NMR: emerging ideas and new frontiers. J Magn Reson, 2014. 241(0): p. 18-31. http://www.ncbi.nlm.nih.gov/pubmed/24656077	nmrlearner	News from NMR blogs	0	06-11-2014 07:41 PM
(1)H-Detected (13)C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR. (1)H-Detected (13)C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR. (1)H-Detected (13)C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR. J Am Chem Soc. 2011 May 6; Authors: Lee JH, Sekhar A, Cavagnero S NMR is a powerful yet intrinsically insensitive technique. The applicability of NMR to chemical and biological systems would be substantially extended by new approaches going beyond current signal-to-noise capabilities. Here, we exploit the large enhancements arising from (13)C photochemically induced dynamic nuclear...	nmrlearner	Journal club	0	05-10-2011 05:11 PM
1H-Detected 13C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR 1H-Detected 13C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR Jung Ho Lee, Ashok Sekhar and Silvia Cavagnero http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja111613c/aop/images/medium/ja-2010-11613c_0005.gif Journal of the American Chemical Society DOI: 10.1021/ja111613c http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/jacsat/~4/nDw3hSNxR80	nmrlearner	Journal club	0	05-06-2011 05:57 PM
[NMR paper] Sensitivity enhancement in two-dimensional solid-state NMR spectroscopy by transverse Sensitivity enhancement in two-dimensional solid-state NMR spectroscopy by transverse mixing. Related Articles Sensitivity enhancement in two-dimensional solid-state NMR spectroscopy by transverse mixing. Chemphyschem. 2004 Jun 21;5(6):863-8 Authors: Tycko R The sensitivity of two-dimensional (2D) 13C-13C solid-state NMR spectroscopy under magic-angle spinning (MAS) is shown to be enhanced by the use of transverse polarization transfer in place of the conventional longitudinal polarization transfer. Experimental results are reported for 2D...	nmrlearner	Journal club	0	11-24-2010 09:51 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is Off Trackbacks are Off Pingbacks are Off Refbacks are Off