The observation of 1H spin noise in relation to prior established mag- netization and radiation damping has revealed a correlated dynamics. The spin noise of methyl satellites in 13C-enriched methanol was observed in the presence of an antiphase magnetization, created by the combination of 1H–13C J coupling evolution and radiofrequency (RF) ulses. A gradient pulse was applied to remove residue spin coherence coming from the RF pulses, and as a result spin noise phenomena were uncovered. While magnetization was in an inverted metastable state, the spin– spin relaxation time was shortened to prevent a super radiation burst. The relation between magnetization, radiation amping, and absorption or emission of the spin noise of methyl satellites has been studied. In relation to agnetization and radiation damping, spin noise bump and dip have been observed simultaneously in the same molecule. Both can be created through a proper inversion of magnetization. The revealed spin noise dynamics of spin system coupling to the probe circuit via radiation damping allows performance of a transformation from dip into bump by proper application of pulses combined with 1H–13C J coupling evolution.
[NMR paper] Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
Related Articles Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
J Am Chem Soc. 2013 Feb 14;
Authors: Anderson KM, Esadze A, Manoharan M, Bruschweiler R, Gorenstein DG, Iwahara J
Abstract
Ion pairing is one of the most fundamental chemical interactions and is essential for molecular recognition by biological macromolecules. From an experimental standpoint, very little is known to date about ion-pair...
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02-15-2013 05:21 PM
[NMR paper] Observation of scalar nuclear spin-spin coupling in van der Waals complexes.
From Mendeley Biomolecular NMR group:
Observation of scalar nuclear spin-spin coupling in van der Waals complexes.
Proceedings of the National Academy of Sciences of the United States of America (2012). Volume: 109, Issue: 31. Pages: 12393-7. Micah P Ledbetter, Giacomo Saielli, Alessandro Bagno, Nhan Tran, Michael V Romalis et al.
Scalar couplings between covalently bound nuclear spins are a ubiquitous feature in nuclear magnetic resonance (NMR) experiments, imparting valuable information to NMR spectra regarding molecular structure and conformation. Such couplings arise due to a...
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11-22-2012 11:49 AM
[NMR paper] Observation of scalar nuclear spin-spin coupling in van der Waals complexes.
From Mendeley Biomolecular NMR group:
Observation of scalar nuclear spin-spin coupling in van der Waals complexes.
Proceedings of the National Academy of Sciences of the United States of America (2012). Volume: 109, Issue: 31. Pages: 12393-7. Micah P Ledbetter, Giacomo Saielli, Alessandro Bagno, Nhan Tran, Michael V Romalis et al.
Scalar couplings between covalently bound nuclear spins are a ubiquitous feature in nuclear magnetic resonance (NMR) experiments, imparting valuable information to NMR spectra regarding molecular structure and conformation. Such couplings arise due to a...
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10-29-2012 12:57 AM
Methanol Strengthens Hydrogen Bonds and Weakens Hydrophobic Interactions in Proteins - A Combined Molecular Dynamics and NMR study.
Methanol Strengthens Hydrogen Bonds and Weakens Hydrophobic Interactions in Proteins - A Combined Molecular Dynamics and NMR study.
Methanol Strengthens Hydrogen Bonds and Weakens Hydrophobic Interactions in Proteins - A Combined Molecular Dynamics and NMR study.
J Phys Chem B. 2011 May 2;
Authors: Hwang S, Shao Q, Williams H, Hilty C, Gao YQ
A combined simulation and experimental study was performed to investigate how methanol affects the structure of a model peptide BBA5. BBA5 forms a stable ?-hairpin-?-helix structure in aqueous solutions....
Signal enhancement in protein NMR using the spin-noise tuning optimum
Signal enhancement in protein NMR using the spin-noise tuning optimum
Abstract We have assessed the potential of an alternative probe tuning strategy based on the spin-noise response for application in common high-resolution multi-dimensional biomolecular NMR experiments with water signal suppression on aqueous and salty samples. The method requires the adjustment of the optimal tuning condition, which may be offset by several 100 kHz from the conventional tuning settings using the noise response of the water protons as an indicator. Although the radio frequency-pulse durations are...
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10-09-2010 03:03 AM
Signal enhancement in protein NMR using the spin-noise tuning optimum.
Signal enhancement in protein NMR using the spin-noise tuning optimum.
Signal enhancement in protein NMR using the spin-noise tuning optimum.
J Biomol NMR. 2010 Oct 6;
Authors: Nausner M, Goger M, Bendet-Taicher E, Schlagnitweit J, Jerschow A, Müller N
We have assessed the potential of an alternative probe tuning strategy based on the spin-noise response for application in common high-resolution multi-dimensional biomolecular NMR experiments with water signal suppression on aqueous and salty samples. The method requires the adjustment of the...
The Observation and Dynamics of 1H NMR Spin Noise in Methanol
Linear Mode
