BioNMR
NMR aggregator & online community since 2003
BioNMR    
Learn or help to learn NMR - get free NMR books!
 

Go Back   BioNMR > NMR community > News from NMR blogs
Advanced Search
Home Forums Wiki NMR feeds Downloads Register Today's Posts



Jobs Groups Conferences Literature Pulse sequences Software forums Programs Sample preps Web resources BioNMR issues


Webservers
NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


Reply
 
Thread Tools Search this Thread Rating: Thread Rating: 1 votes, 5.00 average. Display Modes
  #1  
Old 09-10-2010, 12:58 PM
nmrlearner's Avatar
Senior Member
 
Join Date: Jan 2005
Posts: 23,734
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 193,617
Downloads: 0
Uploads: 0
Default NMR paper in Science

NMR paper in Science

D.M. Korzhnev, T.L. Religa, W.Banachewicz, A.R. Fersht, L.E. Kay, "A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution", Science 329 (2010) 1312-1316. http://dx.doi.org/10.1126/science.1191723

Abstract: "Proteins can sample conformational states that are critical for function but are seldom detected directly because of their low occupancies and short lifetimes. In this work, we used chemical shifts and bond-vector orientation constraints obtained from nuclear magnetic resonance relaxation dispersion spectroscopy, in concert with a chemical shift–based method for structure elucidation, to determine an atomic-resolution structure of an "invisible" folding intermediate of a small protein module: the FF domain. The structure reveals non-native elements preventing formation of the native conformation in the carboxyl-terminal part of the protein. This is consistent with the kinetics of folding in which a well-structured intermediate forms rapidly and then rearranges slowly to the native state. The approach introduces a general strategy for structure determination of low-populated and transiently formed protein states."

This research article by Lewis Kay (University of Toronto) and colleagues is also accompanied by the Science Perspective

H.M. Al-Hashimi, "Exciting Structures", Science 329 (2010) 1295-1296. http://dx.doi.org/10.1126/science.1195571



Read complete story on NMR900 blog
Reply With Quote


Did you find this post helpful? Yes | No

Reply
Similar Threads
Thread Thread Starter Forum Replies Last Post
[NMR900 blog] NMR paper in Nature
NMR paper in Nature G. Bouvignies, P. Vallurupalli, D.F. Hansen, B.E. Correia, O. Lange, A. Bah, R.M. Vernon, F.W. Dahlquist, D. Baker & L.E. Kay, "Solution structure of a minor and transiently formed state of a T4 lysozyme mutant," Nature 477 (2011) 111–114. http://dx.doi.org/10.1038/nature10349https://blogger.googleusercontent.com/tracker/8663203727601106205-5646954509437191595?l=nmr900.blogspot.com Read complete story on NMR900 blog
nmrlearner News from NMR blogs 0 09-10-2011 08:52 PM
[NMR tweet] #thatawkwardmomentwhen i wrote down "Nuclear Magnetic Resonance spectre" on my chemistry paper..
#thatawkwardmomentwhen i wrote down "Nuclear Magnetic Resonance spectre" on my chemistry paper.. Published by woch_ym (woch ??) on 2011-02-21T15:16:13Z Source: Twitter
nmrlearner Twitter NMR 0 02-21-2011 03:18 PM
[NMR900 blog] NMR paper in Nature Structural & Molecular Biology
NMR paper in Nature Structural & Molecular Biology L.A. Freiburger, O.M. Baettig, T. Sprules, A.M. Berghuis, K. Auclair, A.K. Mittermaier, "Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme," Nature Structural & Molecular Biology (2011) online. http://dx.doi.org/10.1038/nsmb.1978 https://blogger.googleusercontent.com/tracker/8663203727601106205-794484937251380301?l=nmr900.blogspot.com Read complete story on NMR900 blog
nmrlearner News from NMR blogs 0 02-11-2011 08:31 AM
[NMR900 blog] NMR paper in Angewandte Chemie
NMR paper in Angewandte Chemie L. Shi, I. Kawamura, K.-H. Jung, L.S. Brown, and V. Ladizhansky, "Conformation of a Seven-Helical Transmembrane Photosensor in the Lipid Environment," Angewandte Chemie International Edition (2011) online. http://dx.doi.org/10.1002/anie.201004422 https://blogger.googleusercontent.com/tracker/8663203727601106205-792265230054630157?l=nmr900.blogspot.com Read complete story on NMR900 blog
nmrlearner News from NMR blogs 0 12-31-2010 07:40 AM
[CNS Yahoo group] Call For Research Paper - IJSER
Call For Research Paper - IJSER International Journal of Scientific and Engineering Research (IJSER)(ISSN 2229-5518) The International Journal of Scientific & Engineering Research is an open More...
nmrlearner News from other NMR forums 1 11-19-2010 11:39 AM
[NMR tweet] im doing a paper on Nuclear magnetic resonance (NMR) spectroscopy. What are some issu
im doing a paper on Nuclear magnetic resonance (NMR) spectroscopy. What are some issues i shoul http://www.mritechnicianprograms.com/?p=154 Published by radiologyschool (radiology schools) on 2010-10-18T22:29:12Z Source: Twitter
nmrlearner Twitter NMR 0 10-18-2010 10:32 PM
NMR paper in Nature
NMR paper in Nature A.M. Ruschak, T.L. Religa, S. Breuer, S. Witt and L.E. Kay, "The proteasome antechamber maintains substrates in an unfolded state," Nature 467 (2010) 868–871. http://dx.doi.org/10.1038/nature09444 https://blogger.googleusercontent.com/tracker/8663203727601106205-6883737347430659051?l=nmr900.blogspot.com Read complete story on NMR900 blog
nmrlearner Journal club 0 10-14-2010 05:01 PM



Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off



BioNMR advertisements to pay for website hosting and domain registration. Nobody does it for us.



Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Copyright, BioNMR.com, 2003-2013
Search Engine Friendly URLs by vBSEO 3.6.0

All times are GMT. The time now is 01:16 AM.


Map