Dutta, Prasanta, Gary V. Martinez, and Robert J. Gillies. “Nanodiamond as a New Hyperpolarizing Agent and Its 13C MRS.” The Journal of Physical Chemistry Letters 5, no. 3 (February 6, 2014): 597–600.
In this work, we have hyperpolarized carbonaceous nanoparticles (D ? 10 nm), that is, “nanodiamonds”, with 1.1% 13C (natural abundance) using dynamic nuclear polarization (DNP). The polarization buildup curve showed a signal enhancement with relative intensity up to 4700 at 1.4 K and 100 mW microwave power. 13C magnetic resonance spectra (MRS) were obtained from the sample at 7 T, and the signal decayed with a T1 of 55 ± 3s. Notably, polarization was possible in the absence of added radical, consistent with previous results showing endogenous unpaired electrons in natural nanodiamonds. These likely contribute to the shorter T1’s compared to those of highly pure diamond. Despite the relatively short T1, these observations suggest that natural nanodiamonds may be useful for in vivo applications.
Persistent Radicals of Self-assembled Benzophenone bis-Urea Macrocycles: Characterization and Application as a Polarizing Agent for Solid-state DNP MAS Spectroscopy #DNPNMR #NMR
From The DNP-NMR Blog:
Persistent Radicals of Self-assembled Benzophenone bis-Urea Macrocycles: Characterization and Application as a Polarizing Agent for Solid-state DNP MAS Spectroscopy #DNPNMR #NMR
Most commonly nitroxide-based radicals are used in DNP. However, there are many other stable radicals. This one is a UV generated radical that is stable for weeks at room temperature. In addition it exhibits a fairly narrow linewidth. This radical, in combination with another narrow line radical (BDPA, trityl, etc.) could make a very efficient polarizing agent when mixed together or even...
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02-12-2018 05:58 PM
Persistent Radicals of Self-assembled Benzophenone bis-Urea Macrocycles: Characterization and Application as a Polarizing Agent for Solid-state DNP MAS Spectroscopy #DNPNMR
From The DNP-NMR Blog:
Persistent Radicals of Self-assembled Benzophenone bis-Urea Macrocycles: Characterization and Application as a Polarizing Agent for Solid-state DNP MAS Spectroscopy #DNPNMR
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DeHaven, B.A., et al., Persistent Radicals of Self-assembled Benzophenone bis-Urea Macrocycles: Characterization and Application as a Polarizing Agent for Solid-state DNP MAS Spectroscopy. Chemistry, 2017. 23(34): p. 8315-8319.
https://www.ncbi.nlm.nih.gov/pubmed/28423212
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10-05-2017 01:01 AM
Nanodiamond-enhanced MRI via in situ hyperpolarization
From The DNP-NMR Blog:
Nanodiamond-enhanced MRI via in situ hyperpolarization
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Waddington, D.E.J., et al., Nanodiamond-enhanced MRI via in situ hyperpolarization. Nat Commun, 2017. 8: p. 15118.
https://www.ncbi.nlm.nih.gov/pubmed/28443626
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09-23-2017 05:52 AM
Hyperpolarized Nanodiamond Surfaces #DNPNMR
From The DNP-NMR Blog:
Hyperpolarized Nanodiamond Surfaces #DNPNMR
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Rej, E., et al., Hyperpolarized Nanodiamond Surfaces. J Am Chem Soc, 2017. 139(1): p. 193-199.
https://www.ncbi.nlm.nih.gov/pubmed/28009158
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02-15-2017 03:40 PM
Cucurbit[6]uril is an ultrasensitive (129)Xe NMR contrast agent
From The DNP-NMR Blog:
Cucurbituril is an ultrasensitive (129)Xe NMR contrast agent
Wang, Y. and I.J. Dmochowski, Cucurbituril is an ultrasensitive (129)Xe NMR contrast agent. Chem Commun (Camb), 2015. 51(43): p. 8982-5.
http://www.ncbi.nlm.nih.gov/pubmed/25929681
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06-11-2015 05:15 AM
Hyperpolarized Nanodiamond with Long Spin Relaxation Times
From The DNP-NMR Blog:
Hyperpolarized Nanodiamond with Long Spin Relaxation Times
Rej E, Gaebel T, Boele T, Waddington D, Reilly D. Hyperpolarized Nanodiamond with Long Spin Relaxation Times. ARXIV. 2015.
http://arxiv.org/abs/1502.06214
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05-28-2015 12:56 AM
[NMR paper] Atomic mapping of the interactions between the antiviral agent cyanovirin-N and oligo
Atomic mapping of the interactions between the antiviral agent cyanovirin-N and oligomannosides by saturation-transfer difference NMR.
Related Articles Atomic mapping of the interactions between the antiviral agent cyanovirin-N and oligomannosides by saturation-transfer difference NMR.
Biochemistry. 2004 Nov 9;43(44):13926-31
Authors: Sandström C, Berteau O, Gemma E, Oscarson S, Kenne L, Gronenborn AM
The minimum oligosaccharide structure required for binding to the potent HIV-inactivating protein cyanovirin-N (CV-N) was determined by...
Nanodiamond as a New Hyperpolarizing Agent and Its 13C MRS #DNPNMR
Linear Mode
