It's been over 6 weeks since my last post on this blog but don’t worry, I haven’t been idle. On the contrary, I have a very good excuse for this lack of posts: We all at Mestrelab have been working very hard trying to get version 6.0 of Mnova finished. Now I’m delighted to announce that we have done it and version 6.0 is finally available for download from our Web site. This is certainly a major upgrade of the software in which we have put a lot of work and passion. It brings a number of enhancements and bug fixes but most significantly are the following new developments:
Yes, Mnova speaks a new language now, not just NMR. Since its conception, Mnova was Multi-document, Multi-Page, Multi-Platform and designed to become Multi-Technique, which it has now done
GSD (Global Spectral Deconvolution)
I have already blogged about it, but now GSD is finally available so that you all can try it and play with it. We are confident that this new powerful analysis tool will open new avenues in many NMR fields
NMR Line Fitting (Deconvolution)
Even though GSD is a fully automatic spectral deconvolution algorithm, a general purpose line fitting (deconvolution) module is always useful. In an effort to maximize user experience, we have developed a powerful, yet easy to use Graphical User Interface which makes possible both the manual and automatic adjustment of any peaks parameters (i.e. peaks positions, heights, line widths, shapes). I will talk more about it in a new post in a few days
NMR Data Analysis Module
Designed for the analysis of arrayed NMR experiments such as DOSY, Relaxation (T1, T2), kinetics, metabonomics, reaction monitoring, etc. This new module includes, among other features, the capability to apply reliable and fast non linear fitting (including specialized mono-exponential fitting), plotting of the experimental and fitted data, etc
Well, this list is not a fair account of all the number of new things implemented in this version. For a detailed list you could check out the ‘What’s new in 6.0'.
From here I encourage you to try this new version and experiment with the new tools. You can download an evaluation version from our website (at www.mestrelab.com). If for some reason your license has already expired, please do not hesitate to get in touch with us at Mestrelab, we will be delighted to supply a license for the software. In the meantime, I can only add that in the next few days I will be creating new posts where I will be revealing in detail each and every new tool of this brand new version as well as some innovative and interesting applications
15N-NMR relaxation data of protein fitting with Modelfree anaylsis
HELLO Every one
my question is ,, i fitted my data on modelfree ,,i get output file mfout
which one is best value for order parameter (S2, S2F,S2S,) in this two
1- fit value ---
2-sim_value
in these two which one i write in my data
Biomolecular NMR data analysis.
Biomolecular NMR data analysis.
Related Articles Biomolecular NMR data analysis.
Prog Nucl Magn Reson Spectrosc. 2010 May;56(4):329-45
Authors: Gryk MR, Vyas J, Maciejewski MW
nmrlearner
Journal club
0
10-19-2010 04:51 PM
[Question from NMRWiki Q&A forum] How to process DOSY data in Mnova?
How to process DOSY data in Mnova?
Hi we have a DOSY dataset aquired using Doneshot.c sequence on a varian instrument.
Will MNOVA process the dataset?
Thanks!
nmrlearner
News from other NMR forums
0
08-25-2010 04:37 AM
[NMR analysis blog] Binning and NMR Data Analysis
Binning and NMR Data Analysis
Yesterday I mentioned that many NMR arrayed experiments suffer from unwanted chemical shift variations due to fluctuations in experimental conditions such as sample temperature, pH, ionic strength, etc. This phenomenon is very common in NMR spectra of e.g. biofluids (metabonomics/metabolomics) but also exists in many other experiments such us Relaxation, Kinetics and PFG NMR spectra (diffusion).
This problem negatively affects the reliability of quantitation using, for instance, peak heights, and for this reason integration is, in general, a more robust...
nmrlearner
News from NMR blogs
0
08-21-2010 09:12 PM
Biomolecular NMR Data Analysis
Biomolecular NMR Data Analysis
Publication year: 2010
Source: Progress in Nuclear Magnetic Resonance Spectroscopy, In Press, Accepted Manuscript, Available online 2 March 2010</br>
Michael R., Gryk , Jay, Vyas , Mark W., Maciejewski</br>
More...
Mnova 6.0, at last! GSD, Line Fitting, Data Analysis, handling of LC/GC/MS data and m
Linear Mode
