Hyperpolarization by Dissolution Dynamic Nuclear Polarization is usually achieved by monochromatic microwave irradiation of the ESR spectrum of free radicals embedded in glasses at 1.2 K and 3.35 T. Hovav et al. (2014) have recently shown that by using frequency-modulated (rather than monochromatic) microwave irradiation one can improve DNP at 3.35 T in the temperature range 10–50 K. We show in this Letter that this is also true under Dissolution-DNP conditions at 1.2 K and 6.7 T. We demonstrate the many virtues of using frequency-modulated microwave irradiation: higher polarizations, faster build-up rates, lower radical concentrations, less paramagnetic broadening, more efficient cross-polarization, and less critical frequency adjustments.
Microwave frequency modulation to enhance Dissolution Dynamic Nuclear Polarization
From The DNP-NMR Blog:
Microwave frequency modulation to enhance Dissolution Dynamic Nuclear Polarization
Bornet, A., J. Milani, B. Vuichoud, A.J. Perez Linde, G. Bodenhausen, and S. Jannin, Chem. Phys. Lett., 602, (2014)
http://www.sciencedirect.com/science/article/pii/S0009261414002826
nmrlearner
News from NMR blogs
0
12-28-2015 12:26 AM
Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery
From The DNP-NMR Blog:
Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery
Min, H., G. Sekar, and C. Hilty, Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery. ChemMedChem, 2015. 10(9): p. 1559-63.
http://www.ncbi.nlm.nih.gov/pubmed/26315550
nmrlearner
News from NMR blogs
0
10-05-2015 07:08 PM
Cross-polarization for dissolution dynamic nuclear polarization
From The DNP-NMR Blog:
Cross-polarization for dissolution dynamic nuclear polarization
Batel, M., et al., Cross-polarization for dissolution dynamic nuclear polarization. Phys Chem Chem Phys, 2014. 16(39): p. 21407-16.
http://www.ncbi.nlm.nih.gov/pubmed/25182534
nmrlearner
News from NMR blogs
0
10-08-2014 05:52 PM
Cross Polarization for Dissolution Dynamic Nuclear Polarization
From The DNP-NMR Blog:
Cross Polarization for Dissolution Dynamic Nuclear Polarization
Batel, M., et al., Cross Polarization for Dissolution Dynamic Nuclear Polarization. Phys. Chem. Chem. Phys., 2014.
http://dx.doi.org/10.1039/C4CP02696A
nmrlearner
News from NMR blogs
0
08-22-2014 07:27 PM
Hyperpolarization of deuterated metabolites via remote cross-polarization and dissolution dynamic nuclear polarization
From The DNP-NMR Blog:
Hyperpolarization of deuterated metabolites via remote cross-polarization and dissolution dynamic nuclear polarization
Vuichoud, B., et al., Hyperpolarization of deuterated metabolites via remote cross-polarization and dissolution dynamic nuclear polarization. J Phys Chem B, 2014. 118(5): p. 1411-5.
http://www.ncbi.nlm.nih.gov/pubmed/24397585
nmrlearner
News from NMR blogs
0
04-02-2014 11:54 PM
Dynamic nuclear polarization using frequency modulation at 3.34T
From The DNP-NMR Blog:
Dynamic nuclear polarization using frequency modulation at 3.34T
Hovav, Y., et al., Dynamic nuclear polarization using frequency modulation at 3.34T. J Magn Reson, 2013. 238C(0): p. 94-105.
http://www.ncbi.nlm.nih.gov/pubmed/24333831