Chen, H.-Y. and R. Tycko, Low-temperature magnetic resonance imaging with 2.8 ?m isotropic resolution. Journal of Magnetic Resonance, 2018. 287: p. 47-55.
We demonstrate the feasibility of high-resolution 1H magnetic resonance imaging (MRI) at low temperatures by obtaining an MRI image of 20 ?m diameter glass beads in glycerol/water at 28 K with 2.8 ?m isotropic resolution. The experiments use a recently-described MRI apparatus (Moore and Tycko, 2015) with minor modifications. The sample is contained within a radio-frequency microcoil with 150 ?m inner diameter. Sensitivity is additionally enhanced by paramagnetic doping, optimization of the sample temperature, three-dimensional phase-encoding of k-space data, pulsed spin-lock detection of 1H nuclear magnetic resonance signals, and spherical sampling of k-space. We verify that the actual image resolution is 2.7 ± 0.3 ?m by quantitative comparisons of experimental and calculated images. Our imaging approach is compatible with dynamic nuclear polarization, providing a path to significantly higher resolution in future experiments.
Simultaneous and spectroscopic redox molecular imaging of multiple free radical intermediates using dynamic nuclear polarization-magnetic resonance imaging #DNPNMR
From The DNP-NMR Blog:
Simultaneous and spectroscopic redox molecular imaging of multiple free radical intermediates using dynamic nuclear polarization-magnetic resonance imaging #DNPNMR
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Hyodo, F., et al., Simultaneous and spectroscopic redox molecular imaging of multiple free radical intermediates using dynamic nuclear polarization-magnetic resonance imaging. Anal Chem, 2014. 86(15): p. 7234-8.
https://www.ncbi.nlm.nih.gov/pubmed/25036767
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08-17-2017 12:56 AM
[NMR paper] Proton-detected 3D (15)N/(1)H/(1)H isotropic/anisotropic/isotropic chemical shift correlation solid-state NMR at 70kHz MAS.
Proton-detected 3D (15)N/(1)H/(1)H isotropic/anisotropic/isotropic chemical shift correlation solid-state NMR at 70kHz MAS.
Related Articles Proton-detected 3D (15)N/(1)H/(1)H isotropic/anisotropic/isotropic chemical shift correlation solid-state NMR at 70kHz MAS.
Solid State Nucl Magn Reson. 2016 Mar 16;76-77:1-6
Authors: Pandey MK, Yarava JR, Zhang R, Ramamoorthy A, Nishiyama Y
Abstract
Chemical shift anisotropy (CSA) tensors offer a wealth of information for structural and dynamics studies of a variety of chemical and...
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
From The DNP-NMR Blog:
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
This is a very nice review of cavities that are used in EPR, NMR and MRI. So far resonators have not been widely employed in DNP spectroscopy - only in some static DNP experiments. However, it is an intriguing problem that could, if solved, allow using cost-effective solid-state sources for DNP even at high temperatures.
Even if this article is not specifically about resonators for DNP it gives a very nice overview of the...
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12-09-2014 01:07 AM
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
Publication date: November 2014
Source:Progress in Nuclear Magnetic Resonance Spectroscopy, Volume 83</br>
Author(s): Andrew Webb</br>
Cavity resonators are widely used in electron paramagnetic resonance, very high field magnetic resonance microimaging and also in high field human imaging. The basic principles and designs of different forms of cavity resonators including rectangular, cylindrical, re-entrant, cavity magnetrons, toroidal...
[NMR paper] Design of a novel class of protein-based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers.
Design of a novel class of protein-based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary-Button_120x27px_FullText.gif Related Articles Design of a novel class of protein-based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Jan 17;
Authors: Xue S, Qiao J, Pu F, Cameron M, Yang JJ
Abstract
Magnetic...
Low-temperature magnetic resonance imaging with 2.8 ?m isotropic resolution
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