The longitudinal nuclear relaxation time, T1, sets a stringent limit on the range of information that can be obtained from magnetic resonance imaging (MRI) experiments. Long-lived nuclear spin states provide a possibility to extend the timescale over which information can be encoded in magnetic resonance. We introduce a strategy to localize an ensemble of molecules for a significantly extended duration (~30 times longer than T1 in this example), using a spatially selective conversion between magnetization and long-lived singlet order. An application to tagging and transport is proposed.
Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR
From The DNP-NMR Blog:
Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR
Buratto, R., et al., Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR. ChemMedChem, 2014: p. n/a-n/a.
http://www.ncbi.nlm.nih.gov/pubmed/25196781
nmrlearner
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09-27-2014 01:54 AM
Long-lived localization in magnetic resonance imaging
From The DNP-NMR Blog:
Long-lived localization in magnetic resonance imaging
Dumez, J.N., et al., Long-lived localization in magnetic resonance imaging. J Magn Reson, 2014. 246C(0): p. 27-30.
http://www.ncbi.nlm.nih.gov/pubmed/25063953
nmrlearner
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09-15-2014 07:13 PM
Storage of nuclear magnetization as long-lived singlet order in low magnetic field
From The DNP-NMR Blog:
Storage of nuclear magnetization as long-lived singlet order in low magnetic field
This week I will catch up with some articles that were published in the Proceedings of the National Academy of Sciences that slipped through the crack.
nmrlearner
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07-21-2014 05:32 PM
Magnetic Resonance Force Microscopy Detected Long-Lived Spin Magnetization
From The DNP-NMR Blog:
Magnetic Resonance Force Microscopy Detected Long-Lived Spin Magnetization
Chen, L., et al., Magnetic Resonance Force Microscopy Detected Long-Lived Spin Magnetization. Magnetics, IEEE Transactions on, 2013. 49(7): p. 3528-3532.
http://dx.doi.org/10.1109/TMAG.2013.2239268
nmrlearner
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08-23-2013 02:29 PM
Design of a 13C magnetic resonance probe using a deuterated methoxy group as a long-lived hyperpolarization unit
From the The DNP-NMR Blog:
Design of a 13C magnetic resonance probe using a deuterated methoxy group as a long-lived hyperpolarization unit
Doura, T., et al., Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit. Angew. Chem. Int. Ed., 2012. 51(40): p. 10114-10117.
http://www.ncbi.nlm.nih.gov/pubmed/22961955
nmrlearner
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04-15-2013 08:52 AM
Long-Lived States to Monitor Protein Unfolding by Proton NMR.
Long-Lived States to Monitor Protein Unfolding by Proton NMR.
Long-Lived States to Monitor Protein Unfolding by Proton NMR.
Chemphyschem. 2011 Aug 31;
Authors: Bornet A, Ahuja P, Sarkar R, Fernandes L, Hadji S, Lee SY, Haririnia A, Fushman D, Bodenhausen G, Vasos PR
Abstract
The relaxation of long-lived states (LLS) corresponds to the slow return to statistical thermal equilibrium between symmetric and antisymmetric proton spin states. This process is remarkably sensitive to the presence of external spins and can be used to obtain...
nmrlearner
Journal club
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09-02-2011 05:40 PM
Long-Lived Coherences for Line-Narrowing in High-Field NMR
Long-Lived Coherences for Line-Narrowing in High-Field NMR
Publication year: 2010
Source: Progress in Nuclear Magnetic Resonance Spectroscopy, In Press, Accepted Manuscript, Available online 21 October 2010</br>
Riddhiman, Sarkar , Puneet, Ahuja , Paul R., Vasos , Aurélien, Bornet , Olivier, Wagnières , ...</br>
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nmrlearner
Journal club
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10-22-2010 07:34 AM
Long-Lived Coherences for Homogeneous Line Narrowing in Spec
Long-Lived Coherences for Homogeneous Line Narrowing in Spec
Physical Review Letters publication on application of long-lived coherences to line-narrowing in NMR by Dr. Geoffrey Bodenhausen and his group.
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Long-lived localization in magnetic resonance imaging
Linear Mode
