The most detailed proteomics study to date of the human embryonic stem cell proteome has identified 3184 proteins, including post-translationally modified proteins and known stem cell markers.
Two highly detailed maps of the human proteome released at same time
Two highly detailed maps of the human proteome released at same time
http://www.spectroscopynow.com/common/images/thumbnails/146483f269e.jpgTwo independent research collaborations have released highly detailed maps of the human proteome in the same publication, identifying a high proportion of the proteins encoded by the human genome.
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05-29-2014 09:35 PM
[NMR paper] Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates.
Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates.
Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates.
Chemistry. 2013 Aug 12;
Authors: Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone EM, Fattorusso R
Abstract
Get well prune: The C-terminal third domain of h-prune is largely unfolded and involved in relevant protein-protein interactions, particularly with...
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08-14-2013 05:24 PM
Long-term stability of human proteome
Long-term stability of human proteome
http://www.spectroscopynow.com/common/images/thumbnails/13be29897a7.jpgThe abundances of 31 major proteins in human plasma, measured by selected reaction monitoring mass spectrometry, remained remarkably steady over 4 months, strengthening their case to be used as disease biomarkers.
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02-03-2013 09:08 AM
NMR Studies of the Interactionbetween Human Programmed Cell Death 5 and Human p53
NMR Studies of the Interactionbetween Human Programmed Cell Death 5 and Human p53
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/bi201822x/aop/images/medium/bi-2011-01822x_0006.gif
Biochemistry
DOI: 10.1021/bi201822x
http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/bichaw/~4/EP2xmvNmj2Q
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03-20-2012 10:52 PM
Site-Specific ?- and ?-Torsion Angle Determination in a Uniformly/Extensively 13C- and 15N-Labeled Peptide
Site-Specific ?- and ?-Torsion Angle Determination in a Uniformly/Extensively 13C- and 15N-Labeled Peptide
Publication year: 2011
Source: Journal of Magnetic Resonance, In Press, Accepted Manuscript, Available online 17 August 2011</br>
Sungsool, Wi , Justin, Spano</br>
A solid-state rotational-echo double resonance (REDOR) NMR method was introduced to identify the ?- and ?-torsion angle from a 1H–15N or 1H–13C? spin system of alanine-like residues in a selectively, uniformly, or extensively 15N-/13C-labeled peptide. When a C?(i) or a 15N peak is site-specifically obtainable in the...
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08-18-2011 03:52 AM
[NMR paper] NMR structure and regulated expression in APL cell of human SH3BGRL3.
NMR structure and regulated expression in APL cell of human SH3BGRL3.
Related Articles NMR structure and regulated expression in APL cell of human SH3BGRL3.
FEBS Lett. 2005 May 23;579(13):2788-94
Authors: Xu C, Zheng P, Shen S, Xu Y, Wei L, Gao H, Wang S, Zhu C, Tang Y, Wu J, Zhang Q, Shi Y
SH3 domain binding glutamic acid-rich protein like 3 (SH3BGRL3) is the new member of thioredoxin (TRX) super family, whose posttranslational modified form was identified as tumor necrosis factor alpha (TNF-alpha) inhibitory protein, TIP-B1. In this paper,...
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11-25-2010 08:21 PM
[NMR paper] NMR structure of the 3' stem-loop from human U4 snRNA.
NMR structure of the 3' stem-loop from human U4 snRNA.
Related Articles NMR structure of the 3' stem-loop from human U4 snRNA.
Nucleic Acids Res. 2002 Oct 15;30(20):4371-9
Authors: Comolli LR, Ulyanov NB, Soto AM, Marky LA, James TL, Gmeiner WH
The NMR structure of the 3' stem-loop (3'SL) from human U4 snRNA was determined to gain insight into the structural basis for conservation of this stem-loop sequence from vertebrates. 3'SL sequences from human, rat, mouse and chicken U4 snRNA each consist of a 7 bp stem capped by a UACG tetraloop. No...
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11-24-2010 08:58 PM
[NMR paper] 13C-NMR investigation of protein synthesis during apoptosis in human leukemic cell li
13C-NMR investigation of protein synthesis during apoptosis in human leukemic cell lines.
Related Articles 13C-NMR investigation of protein synthesis during apoptosis in human leukemic cell lines.
J Cell Physiol. 1999 Oct;181(1):147-52
Authors: Scott CE, Adebodun F
In order to evaluate the role of protein synthesis in apoptosis, (13)C-NMR has been used to study the levels of protein synthesis in three different human leukemic cell lines in the presence and absence of dexamethasone-induced apoptosis. Measurements were done on one...
Human stem cell proteome extensively mined
The most detailed proteomics study to date of the human embryonic stem cell proteome has identified 3184 proteins, including post-translationally modified proteins and known stem cell markers.
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