A systematic study of the performance of the dissolution process in dissolution-DNP is presented. A relatively simple set of modifications is made to the standard Hypersense dissolution system to enable polarization of large volume samples. These consist of a large volume sample cup along with supporting modifications to the dissolution head and related components. Additional modifications were made to support the mapping of the temperature/pressure space of the dissolution process as well as enabling the use of large volumes of solvent and improving the robustness of the system. No loss of polarization was observed as sample size was increased to the 1 g capacity of the large volume cup and for a dilution factor as low as 1:10.
Protein folding studied by dissolution dynamic nuclear polarization
From The DNP-NMR Blog:
Protein folding studied by dissolution dynamic nuclear polarization
Chen, H.Y., M. Ragavan, and C. Hilty, Protein folding studied by dissolution dynamic nuclear polarization. Angew Chem Int Ed Engl, 2013. 52(35): p. 9192-5.
http://www.ncbi.nlm.nih.gov/pubmed/23857756
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04-07-2014 06:59 PM
[NMR paper] Performance tuning non-uniform sampling for sensitivity enhancement of signal-limited biological NMR.
Performance tuning non-uniform sampling for sensitivity enhancement of signal-limited biological NMR.
Related Articles Performance tuning non-uniform sampling for sensitivity enhancement of signal-limited biological NMR.
J Biomol NMR. 2014 Mar 29;
Authors: Palmer MR, Wenrich BR, Stahlfeld P, Rovnyak D
Abstract
Non-uniform sampling (NUS) has been established as a route to obtaining true sensitivity enhancements when recording indirect dimensions of decaying signals in the same total experimental time as traditional uniform...
Host-Guest Complexes as Water-Soluble High-Performance DNP Polarizing Agents
From The DNP-NMR Blog:
Host-Guest Complexes as Water-Soluble High-Performance DNP Polarizing Agents
Mao, J., et al., Host-Guest Complexes as Water-Soluble High-Performance DNP Polarizing Agents. J Am Chem Soc, 2013. 135(51): p. 19275-81.
http://www.ncbi.nlm.nih.gov/pubmed/24279469
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01-10-2014 06:01 PM
Construction and performance of an NMR tube with a sample cavity formed within magnetic susceptibility-matched glass.
Construction and performance of an NMR tube with a sample cavity formed within magnetic susceptibility-matched glass.
Construction and performance of an NMR tube with a sample cavity formed within magnetic susceptibility-matched glass.
J Magn Reson. 2011 Apr;209(2):167-73
Authors: Takeda M, Hallenga K, Shigezane M, Waelchli M, Löhr F, Markley JL, Kainosho M
We describe the construction and performance of an NMR tube with a magnetic susceptibility matched sample cavity that confines the solution within the detection zone in the axial direction and...
On the Performance of Spin Diffusion NMR Techniques in Oriented Solids: Prospects for
On the Performance of Spin Diffusion NMR Techniques in Oriented Solids: Prospects for Resonance Assignments and Distance Measurements from Separated Local Field Experiments.
Related Articles On the Performance of Spin Diffusion NMR Techniques in Oriented Solids: Prospects for Resonance Assignments and Distance Measurements from Separated Local Field Experiments.
J Phys Chem B. 2010 Oct 11;
Authors: Traaseth NJ, Gopinath T, Veglia G
NMR spin diffusion experiments have the potential to provide both resonance assignment and internuclear...
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10-13-2010 02:18 PM
Bruker Introduces Icon, a High-Performance Desktop MRI Syste
Bruker Introduces Icon, a High-Performance Desktop MRI Syste
Bruker Corporation today announces the introduction of the Iconâ„¢ , a new easy-to-use 1 Tesla desktop MRI scanner that combines simplicity with compact dimensions, in order to bring preclinical magnetic resonance imaging (MRI) within reach for a broader range of molecular imaging laboratories.
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Enhanced performance large volume dissolution-DNP
Linear Mode
