Instrumentation for DNP-NMR spectroscopy has many similar components to instrumentation for EPR spectroscopy. This is a comprehensive review of the current state-of-the-art in EPR instrumentation, covering all aspects from magnet technology, pulse generation, detection and resonator design.
Reijerse, Edward, and Anton Savitsky. “Electron Paramagnetic Resonance Instrumentation.” In EMagRes, edited by Robin K. Harris and Roderick L. Wasylishen, 187–206. Chichester, UK: John Wiley & Sons, Ltd, 2017.
The article gives a general overview of instrumentation commonly used in electron paramagnetic resonance. It includes magnet systems, microwave bridge configurations, and sample cryostats. A special focus has been placed on the discussion of various resonator and sample probe designs used in CW as well as pulsed EPR. Specialized EPR applications such as very high frequency EPR, electrochemistry, stopped flow, and the application to volume limited samples are briefly discussed.
New limits of sensitivity of site-directed spin labeling electron paramagnetic resonance for membrane proteins #DNPNMR
From The DNP-NMR Blog:
New limits of sensitivity of site-directed spin labeling electron paramagnetic resonance for membrane proteins #DNPNMR
A nice overview how spinlabels can be used for structural biology studies. This includes pulsed EPR techniques such as PELDOR (DEER) and ODNP spectroscopy.
Bordignon, Enrica, and Stephanie Bleicken. “New Limits of Sensitivity of Site-Directed Spin Labeling Electron Paramagnetic Resonance for Membrane Proteins.” Biochimica et Biophysica Acta (BBA) - Biomembranes 1860, no. 4 (April 2018): 841–53. https://doi.org/10.1016/j.bbamem.2017.12.009.
Electron Decoupling with Chirped Microwave Pulses for Rapid Signal Acquisition and Electron Saturation Recovery #DNPNMR
From The DNP-NMR Blog:
Electron Decoupling with Chirped Microwave Pulses for Rapid Signal Acquisition and Electron Saturation Recovery #DNPNMR
Barnes, Alexander, Nicholas Alaniva, Edward P. Saliba, Erika L. Sesti, and Patrick T. Judge. “Electron Decoupling with Chirped Microwave Pulses for Rapid Signal Acquisition and Electron Saturation Recovery.” Angewandte Chemie, March 28, 2019.
https://doi.org/10.1002/ange.201900139.
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News from NMR blogs
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05-06-2019 04:47 PM
Electron Paramagnetic Resonance Aids Cancer Drug - News-Medical.net
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News-Medical.net
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Electron Paramagnetic Resonance Aids Cancer Drug
News-Medical.net
Compared with nuclear magnetic resonance (NMR), EPR offers improved sensitivity, and can be used within a shorter time-frame and in larger molecules. EPR can also be used in conjunction with a spin-labeled protein, in which a stable radical is used to ...
Electron Paramagnetic Resonance Aids Cancer Drug - News-Medical.net
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08-30-2017 10:52 AM
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
From The DNP-NMR Blog:
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
This is a very nice review of cavities that are used in EPR, NMR and MRI. So far resonators have not been widely employed in DNP spectroscopy - only in some static DNP experiments. However, it is an intriguing problem that could, if solved, allow using cost-effective solid-state sources for DNP even at high temperatures.
Even if this article is not specifically about resonators for DNP it gives a very nice overview of the...
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12-09-2014 01:07 AM
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging
Publication date: November 2014
Source:Progress in Nuclear Magnetic Resonance Spectroscopy, Volume 83</br>
Author(s): Andrew Webb</br>
Cavity resonators are widely used in electron paramagnetic resonance, very high field magnetic resonance microimaging and also in high field human imaging. The basic principles and designs of different forms of cavity resonators including rectangular, cylindrical, re-entrant, cavity magnetrons, toroidal...
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Journal club
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10-24-2014 07:14 AM
Phase cycling with a 240 GHz, free electron laser-powered electron paramagnetic resonance spectrometer
From the The DNP-NMR Blog:
Phase cycling with a 240 GHz, free electron laser-powered electron paramagnetic resonance spectrometer
This is not an article directly related to DNP spectroscopy. However, it shows the tremendous progress made in the development of high-frequency, high-power sources that can be utilized for high-field EPR and eventually DNP experiments.
<div>Edwards, D.T., et al., Phase cycling with a 240 GHz, free electron laser-powered electron paramagnetic resonance spectrometer. Phys. Chem. Chem. Phys., 2013.
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04-15-2013 08:52 AM
Measurement of rate constants for homodimer subunit exchange using double electronâ??electron resonance and paramagnetic relaxation enhancements
Measurement of rate constants for homodimer subunit exchange using double electronâ??electron resonance and paramagnetic relaxation enhancements
Abstract Here, we report novel methods to measure rate constants for homodimer subunit exchange using double electronâ??electron resonance (DEER) electron paramagnetic resonance spectroscopy measurements and nuclear magnetic resonance spectroscopy based paramagnetic relaxation enhancement (PRE) measurements. The techniques were demonstrated using the homodimeric protein Dsy0195 from the strictly anaerobic bacterium Desulfitobacterium...
Electron Paramagnetic Resonance Instrumentation #DNPNMR
Linear Mode
