NMR structures of polytopic integral membrane proteins.
NMR structures of polytopic integral membrane proteins.
NMR structures of polytopic integral membrane proteins.
Mol Membr Biol. 2011 Aug 2;
Authors: Patching SG
Abstract Membrane proteins represent up to 30% of the proteins in all organisms, they are involved in many biological processes and are the molecular targets for around 50% of validated drugs. Despite this, membrane proteins represent less than 1% of all high-resolution protein structures due to various challenges associated with applying the main biophysical techniques used for...
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08-04-2011 11:41 AM
Solution NMR study of integral membrane proteins.
Solution NMR study of integral membrane proteins.
Solution NMR study of integral membrane proteins.
Curr Opin Chem Biol. 2011 Jun 18;
Authors: Kang C, Li Q
Signals between a cell and its environment are often transmitted through membrane proteins; therefore, many membrane proteins, including G protein-coupled receptors (GPCRs) and ion channels, are important drug targets. Structural information about membrane proteins remains limited owing to challenges in protein expression, purification and the selection of membrane-mimicking systems that will...
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06-21-2011 01:50 PM
[NMR paper] NMR structure of the integral membrane protein OmpX.
NMR structure of the integral membrane protein OmpX.
Related Articles NMR structure of the integral membrane protein OmpX.
J Mol Biol. 2004 Mar 5;336(5):1211-21
Authors: Fernández C, Hilty C, Wider G, Güntert P, Wüthrich K
The structure of the integral membrane protein OmpX from Escherichia coli reconstituted in 60 kDa DHPC micelles (OmpX/DHPC) was calculated from 526 NOE upper limit distance constraints. The structure determination was based on complete sequence-specific assignments for the amide protons and the Val, Leu, and Ile(delta1)...
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11-24-2010 09:25 PM
[Stan NMR blog] FID apodization and peak integral ratios
FID apodization and peak integral ratios
Review of a sometimes controversial point in NMR spectroscopy practice
Source: Stan blog library
nmrlearner
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11-23-2010 07:11 PM
[Question from NMRWiki Q&A forum] Exporting integral data for use in calculations
Exporting integral data for use in calculations
Hello people,
For my internship I am attempting to fully automate monomer composition analysis on Bruker TOPSPIN 2.0 using visual basic and macro's. It's almost fully functional but I've come across the following problem:
I want to use the integral data of a spectrum in calculations (i.e. export them to an excel template) but so far I've found no way of exporting integral data without using the mouse (I can make visual basic simulate mouse clicks, but it's not a method I like using since it makes the program very prone to failure or...
nmrlearner
News from other NMR forums
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11-22-2010 07:08 PM
[NMR paper] Determination of the binding specificity of an integral membrane protein by saturatio
Determination of the binding specificity of an integral membrane protein by saturation transfer difference NMR: RGD peptide ligands binding to integrin alphaIIbbeta3.
Related Articles Determination of the binding specificity of an integral membrane protein by saturation transfer difference NMR: RGD peptide ligands binding to integrin alphaIIbbeta3.
J Med Chem. 2001 Sep 13;44(19):3059-65
Authors: Meinecke R, Meyer B
Saturation transfer difference (STD) NMR is a fast and versatile method to screen compound mixtures in the presence of a receptor...
[Stan NMR blog] Advances in Approximations of Ellipse Perimeters
Advances in Approximations of Ellipse Perimeters
MATH: Analysis of a family of approximations and an uncorrelated announcement of a new record-breaking formula by Mahmood Shalil Ahmadi.
More...
Dawson Integral Approximations
Linear Mode
