Proteins deposited from tear fluid onto contact lenses worn for just one day can be detected and identified, providing a novel route for studying eye conditions.
[NMR paper] Metabolomics of the rat lens: a combined LC-MS and NMR study.
Metabolomics of the rat lens: a combined LC-MS and NMR study.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Metabolomics of the rat lens: a combined LC-MS and NMR study.
Exp Eye Res. 2014 Aug;125:71-8
Authors: Yanshole VV, Snytnikova OA, Kiryutin AS, Yanshole LV, Sagdeev RZ, Tsentalovich YP
Abstract
This work is the first comprehensive report on the quantitative metabolomic composition of the rat lens. Quantitative metabolomic profiles...
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Protein courtship revealed through chemist's lens - Phys.Org
Protein courtship revealed through chemist's lens - Phys.Org
http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcQOKCXJUFn8JH3Fz7hNm0PQ2S3jQHg3sKDkrUjJ5Zd1vybPn96ocPBvEQrkW9nsxo85DzxQn7Ed
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Protein courtship revealed through chemist's lens
Phys.Org
But changes in the protein NMR spectra are small and weak, so finding out whether the trick worked wasn't straightforward. "At first, we didn't know what we were looking at. It appeared to us as uncertainty in the data, and it was extremely time ...
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09-15-2014 07:13 PM
[NMR paper] Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and hig
Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy.
Related Articles Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy.
Invest Ophthalmol Vis Sci. 2003 May;44(5):2047-58
Authors: Satake M, Dmochowska B, Nishikawa Y, Madaj J, Xue J, Guo Z, Reddy DV, Rinaldi PL, Monnier VM
PURPOSE: Metabolomics, or metabolic profiling, is an emerging discipline geared to providing information on a large number of metabolites,...
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11-24-2010 09:01 PM
[NMR paper] Contact model for the prediction of NMR N-H order parameters in globular proteins.
Contact model for the prediction of NMR N-H order parameters in globular proteins.
Related Articles Contact model for the prediction of NMR N-H order parameters in globular proteins.
J Am Chem Soc. 2002 Oct 30;124(43):12654-5
Authors: Zhang F, Brüschweiler R
An analytical relationship is presented for the estimation of NMR S2 order parameters of N-HN vectors of the protein backbone from high-resolution protein structures. The relationship solely depends on close contacts of the peptide plane to the rest of the protein. Application of the...
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[NMR paper] Comparative 1H-NMR studies on the physical state of water in soft contact lens and mo
Comparative 1H-NMR studies on the physical state of water in soft contact lens and mouse lens.
Related Articles Comparative 1H-NMR studies on the physical state of water in soft contact lens and mouse lens.
Biochim Biophys Acta. 1996 Apr 17;1289(3):369-76
Authors: Kuwata K, Era S, Sogami M, Amano H, Nagaoka S, Kato K, Takahashi K, Kitazawa Y, Watari H
The physical state of water in mouse lenses (2-, 4- or 8-wk-old) and soft contact lenses (SCLs, water content from 18.4 to 79.2%) were studied by measuring spin-lattice relaxation times (T1) and...
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[NMR paper] Supramolecular order within the lens: 1H NMR spectroscopic evidence for specific crys
Supramolecular order within the lens: 1H NMR spectroscopic evidence for specific crystallin-crystallin interactions.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Supramolecular order within the lens: 1H NMR spectroscopic evidence for specific crystallin-crystallin interactions.
Exp Eye Res. 1994 Nov;59(5):607-16
Authors: Cooper PG, Aquilina JA, Truscott RJ, Carver JA
alpha-, beta- and gamma-crystallins from bovine lens contain flexible terminal extensions which are...
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[NMR paper] 1H-NMR spectroscopy of beta B2-crystallin from bovine eye lens. Conformation of the N
1H-NMR spectroscopy of beta B2-crystallin from bovine eye lens. Conformation of the N- and C-terminal extensions.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles 1H-NMR spectroscopy of beta B2-crystallin from bovine eye lens. Conformation of the N- and C-terminal extensions.
Eur J Biochem. 1993 Apr 1;213(1):313-20
Authors: Carver JA, Cooper PG, Truscott RJ
1H-NMR spectroscopic studies of a 46-kDa homodimer, beta B2-crystallin,...
Contact lens contaminating proteins identified
Proteins deposited from tear fluid onto contact lenses worn for just one day can be detected and identified, providing a novel route for studying eye conditions.
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