Recently I finished a great book that made me think about different things on a lot of different levels. The book is called The Black Swan and the author is Nassim Nicholas Taleb. In short, a black swan is defined...
Triple resonance three-dimensional protein NMR: Before it became a black box.
Triple resonance three-dimensional protein NMR: Before it became a black box.
Triple resonance three-dimensional protein NMR: Before it became a black box.
J Magn Reson. 2011 Aug 30;
Authors: Bax A
Abstract
Three-dimensional triple resonance experiments have become an integral part of virtually every solution NMR study of proteins. The approach relies on uniform isotopic enrichment of proteins with (13)C and (15)N, and establishes the scalar connectivity pathway between nuclei through the large (1)J(NH), (1)J(CH)(, 1)J(CC), and (1)J(CN)...
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09-03-2011 06:55 PM
Triple resonance three-dimensional protein NMR: Before it became a black box
Triple resonance three-dimensional protein NMR: Before it became a black box
Publication year: 2011
Source: Journal of Magnetic Resonance, In Press, Corrected Proof, Available online 31 August 2011</br>
Ad, Bax</br>
Three-dimensional triple resonance experiments have become an integral part of virtually every solution NMR study of proteins. The approach relies on uniform isotopic enrichment of proteins with 13C and 15N, and establishes the scalar connectivity pathway between nuclei through the large 1JNH, 1JCH, 1JCC, and 1JCN couplings. The magnetization transfer process takes place...
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08-31-2011 07:12 PM
[NMR paper] Design and characterization of libraries of molecular fragments for use in NMR screen
Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets.
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J Chem Inf Comput Sci. 2004 Nov-Dec;44(6):2157-66
Authors: Baurin N, Aboul-Ela F, Barril X, Davis B, Drysdale M, Dymock B, Finch H, Fromont C, Richardson C, Simmonite H, Hubbard RE
We have designed four generations of a low molecular weight fragment library for use in NMR-based screening against protein...
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11-24-2010 10:03 PM
[NMR paper] Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to pro
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Org Biomol Chem. 2004 Mar 7;2(5):725-31
Authors: Tengel T, Fex T, Emtenas H, Almqvist F, Sethson I, Kihlberg J
Identification of compounds from chemical libraries that bind to macromolecules by use of NMR spectroscopy has gained increasing importance during recent years. A simple methodology based on (19)F NMR spectroscopy for the screening of...
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[NMR paper] A structural homologue of colipase in black mamba venom revealed by NMR floating disu
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J Mol Biol. 1998;283(1):205-19
Authors: Boisbouvier J, Albrand JP, Blackledge M, Jaquinod M, Schweitz H, Lazdunski M, Marion D
The solution structure of mamba intestinal toxin 1 (MIT1), isolated from Dendroaspis polylepis polylepis venom, has been determined. This molecule is a cysteine-rich polypeptide...
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[NMR paper] Comparison of black coral skeleton and insect cuticle by a combination of carbon-13 N
Comparison of black coral skeleton and insect cuticle by a combination of carbon-13 NMR and chemical analyses.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Comparison of black coral skeleton and insect cuticle by a combination of carbon-13 NMR and chemical analyses.
Arch Biochem Biophys. 1992 Jan;292(1):107-11
Authors: Holl SM, Schaefer J, Goldberg WM, Kramer KJ, Morgan TD, Hopkins TL
Cross-polarization, magic-angle spinning 13C NMR spectra of skeletal components of...
The Black Swan of Compound Libraries
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