Efficient syntheses of fluorinated leucines, valines and alanines are described. The synthetic routes provide expedient access to various ^(13)C/^(15)N/D isotopologues requiring solely readily available and inexpensive isotope containing reagents such as NaBD(4), carbon-^(13)C dioxide and sodium azide-1-^(15)N. The lightly fluorinated leucines and valines were found to be good substrates for cell-free protein expression and even 3-fluoroalanine, which is highly toxic to bacteria in vivo, could...
[ASAP] 4'-Fluorinated RNA: Synthesis, Structure, and Applications as a Sensitive 19F NMR Probe of RNA Structure and Function
4'-Fluorinated RNA: Synthesis, Structure, and Applications as a Sensitive 19F NMR Probe of RNA Structure and Function
Qiang Li†, Jialiang Chen†, Marko Trajkovski‡§, Yifei Zhou†, Chaochao Fan†, Kuan Lu†, Pingping Tang†, Xuncheng Su†, Janez Plavec*‡§, Zhen Xi†, and Chuanzheng Zhou*†
https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.9b13207/20200226/images/medium/ja9b13207_0007.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.9b13207
http://feeds.feedburner.com/~r/acs/jacsat/~4/t3kReyX_T6M
A comparative study of 1H and 19F Overhauser DNP in fluorinated benzenes
From The DNP-NMR Blog:
A comparative study of 1H and 19F Overhauser DNP in fluorinated benzenes
Neudert, O., et al., A comparative study of 1H and 19F Overhauser DNP in fluorinated benzenes. Phys Chem Chem Phys, 2013. 15(47): p. 20717-26.
http://www.ncbi.nlm.nih.gov/pubmed/24192645
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01-14-2014 02:57 AM
A comparative study of (1)H and (19)F Overhauser DNP in fluorinated benzenes
From The DNP-NMR Blog:
A comparative study of (1)H and (19)F Overhauser DNP in fluorinated benzenes
Neudert, O., et al., A comparative study of (1)H and (19)F Overhauser DNP in fluorinated benzenes. Phys Chem Chem Phys, 2013. 15(47): p. 20717-26.
http://www.ncbi.nlm.nih.gov/pubmed/24192645
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11-28-2013 05:07 AM
[NMR paper] The use of 19F NMR in the study of protein alkylation by fluorinated reactive interme
The use of 19F NMR in the study of protein alkylation by fluorinated reactive intermediates.
Related Articles The use of 19F NMR in the study of protein alkylation by fluorinated reactive intermediates.
Adv Exp Med Biol. 1991;283:735-8
Authors: Harris JW, Anders MW
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08-21-2010 11:16 PM
[NMR paper] NMR studies of fluorinated visual pigment analogs.
NMR studies of fluorinated visual pigment analogs.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles NMR studies of fluorinated visual pigment analogs.
Biochem Biophys Res Commun. 1991 Sep 30;179(3):1337-43
Authors: Colmenares LU, Asato AE, Denny M, Mead D, Zingoni JP, Liu RS
The 19F-nmr chemical shift data of isomeric pigments (11-cis and 9-cis) of four vinyl fluororhodopsins and two trifluororhodopsins have been recorded. When compared with model protonated Schiff...
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08-21-2010 11:12 PM
[NMR paper] NMR studies of fluorinated visual pigment analogs.
NMR studies of fluorinated visual pigment analogs.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles NMR studies of fluorinated visual pigment analogs.
Biochem Biophys Res Commun. 1991 Sep 30;179(3):1337-43
Authors: Colmenares LU, Asato AE, Denny M, Mead D, Zingoni JP, Liu RS
The 19F-nmr chemical shift data of isomeric pigments (11-cis and 9-cis) of four vinyl fluororhodopsins and two trifluororhodopsins have been recorded. When compared with model protonated Schiff...
Synthesis of fluorinated leucines, valines and alanines for use in protein NMR
Linear Mode
