Metal chelation can provide structural stability and form reactive centers in metalloproteins. Approximately one third of known protein structures are metalloproteins, and metal binding, or the lack thereof, is often implicated in disease, making it necessary to be able to study these systems in detail. Peptide-metal complexes are both present in nature and can provide a means to focus on the binding region of a protein and control experimental variables to a high degree. Structural studies of...
[NMR paper] Metal-ion Binding to Host Defense Peptide Piscidin 3 Observed in Phospholipid Bilayers by Magic Angle Spinning Solid-state NMR.
Metal-ion Binding to Host Defense Peptide Piscidin 3 Observed in Phospholipid Bilayers by Magic Angle Spinning Solid-state NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-7315-19-Wiley_FullText_120x30_orange.png Related Articles Metal-ion Binding to Host Defense Peptide Piscidin 3 Observed in Phospholipid Bilayers by Magic Angle Spinning Solid-state NMR.
Chemphyschem. 2019 01 21;20(2):295-301
Authors: Rai RK, De Angelis A, Greenwood A, Opella SJ, Cotten ML
Abstract
Cationic...
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[NMR paper] Studying the assembly of the BAM complex in native membranes by cellular solid-state NMR spectroscopy.
Studying the assembly of the BAM complex in native membranes by cellular solid-state NMR spectroscopy.
Studying the assembly of the BAM complex in native membranes by cellular solid-state NMR spectroscopy.
J Struct Biol. 2017 Nov 29;:
Authors: Pinto C, Mance D, Julien M, Daniels M, Weingarth M, Baldus M
Abstract
Significant progress has been made in obtaining a structural insight into the assembly of the ?-barrel assembly machinery complex (BAM). These crystallography and electron microscopy studies used detergent as a membrane...
[NMR paper] Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and DNP MAS NMR.
Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and DNP MAS NMR.
Related Articles Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and DNP MAS NMR.
J Am Chem Soc. 2015 Oct 9;
Authors: Geiger Y, Gottlieb HE, Akbey Ü, Oschkinat H, Goobes G
Abstract
Smart materials are created in nature at interfaces between biomolecules and solid materials. The ability to probe the structure of functional peptides...
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[NMR paper] Solid-state NMR studies of metal-free SOD1 fibrillar structures.
Solid-state NMR studies of metal-free SOD1 fibrillar structures.
Related Articles Solid-state NMR studies of metal-free SOD1 fibrillar structures.
J Biol Inorg Chem. 2014 Apr 10;
Authors: Banci L, Blaevit O, Cantini F, Danielsson J, Lang L, Luchinat C, Mao J, Oliveberg M, Ravera E
Abstract
Copper-zinc superoxide dismutase 1 (SOD1) is present in the protein aggregates deposited in motor neurons of amyotrophic lateral sclerosis (ALS) patients. ALS is a neurodegenerative disease that can be either sporadic (ca. 90*%) or familial...
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04-11-2014 02:51 PM
[NMR paper] Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods.
Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods.
Related Articles Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods.
J Biomol NMR. 2013 Apr 23;
Authors: Chakravorty DK, Wang B, Lee CW, Guerra AJ, Giedroc DP, Merz KM
Abstract
Correctly calculating the structure of metal coordination sites in a protein during the process of nuclear magnetic resonance (NMR) structure determination and refinement continues to...
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[NMR paper] An NMR method for studying the kinetics of metal exchange in biomolecular systems.
An NMR method for studying the kinetics of metal exchange in biomolecular systems.
Related Articles An NMR method for studying the kinetics of metal exchange in biomolecular systems.
J Biomol NMR. 2002 Aug;23(4):303-9
Authors: Barbieri R, Hore PJ, Luchina C, Pierattelli R
The kinetics of lanthanide (III) exchange for calcium(II) in the C-terminal EF-hand of the protein calbindin D9k have been studied by one-dimensional (1D) stopped-flow NMR. By choosing a paramagnetic lanthanide (Ce3+), kinetics in the sub-second range can be easily measured....
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[NMR paper] NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+
NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump.
Related Articles NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump.
Biochemistry. 1999 Sep 21;38(38):12320-32
Authors: Elshorst B, Hennig M, Försterling H, Diener A, Maurer M, Schulte P, Schwalbe H, Griesinger C, Krebs J, Schmid H, Vorherr T, Carafoli E
The three-dimensional structure of the complex between calmodulin (CaM) and a peptide corresponding to the N-terminal portion of the CaM-binding domain of the...
Studying Peptide-Metal Ion Complex Structures by Solution-State NMR
Linear Mode
