NMR paper Strategies for 1H-detected dynamic nuclear polarisation magic-angle spinning NMR.

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[NMR paper] Strategies for 1H-detected dynamic nuclear polarisation magic-angle spinning NMR.

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08-23-2020, 10:50 AM

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Strategies for 1H-detected dynamic nuclear polarisation magic-angle spinning NMR.

Strategies for 1H-detected dynamic nuclear polarisation magic-angle spinning NMR.

Related Articles Strategies for 1H-detected dynamic nuclear polarisation magic-angle spinning NMR.

Chemistry. 2020 Aug 22;:

Authors: Concistré M, Paul S, Carravetta M, Kuprov I, Williamson PTF

Abstract
Combining dynamic nuclear polarization with proton detection significantly enhances the sensitivity of magic-angle spinning NMR. Here we demonstrate the feasibility of proton- detected experiments with slow (10 kHz) magic angle spinning. The improvement in sensitivity permits the acquisition of indirectly detected *14N spectra allowing biomolecular structures to be characterized without recourse to isotope labelling. This provides a new tool for the structural characterization of environmental and medical samples where isotope labelling is frequently intractable.

PMID: 32827182 [PubMed - as supplied by publisher]

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