Solution Structure and NMR Chemical Shift Perturbations of the Arabidopsis BCCP1 Identify Intersubunit Interactions Potentially Involved in the Assembly of the Heteromeric Acetyl-CoA Carboxylase
 

Solution Structure and NMR Chemical Shift Perturbations of the Arabidopsis BCCP1 Identify Intersubunit Interactions Potentially Involved in the Assembly of the Heteromeric Acetyl-CoA Carboxylase

Biotin carboxyl carrier protein (BCCP) is a subunit of the heteromeric acetyl-CoA carboxylase (htACCase), and it chemically links the two half-reactions that constitute the formation of malonyl-CoA from acetyl-CoA, a critical reaction in fatty acid biosynthesis. Because plants are a major source of edible fats and oils, it is important to understand the structural organization of the plant htACCase, relative to its potential to regulate fatty acid biosynthesis in plant plastids. Moreover, unique...

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