People with the genetic disease cystic fibrosis (CF) often have chronic airway infections and produce airway secretions called sputum. A better understanding of sputum composition is desired in order to track changes in response to CF therapeutics and to improve laboratory models for the study of CF airway infections. The glycosylated protein mucin is a primary component. Along with extracellular DNA, mucin gives rise to the high viscoelasticity of sputum, which inhibits airway clearance and is...
[NMR paper] Compositional and optical characteristics of aqueous brown carbon and HULIS in the eastern Indo-Gangetic Plain using a coupled EEM PARAFAC, FT-IR and (1)H NMR approach
Compositional and optical characteristics of aqueous brown carbon and HULIS in the eastern Indo-Gangetic Plain using a coupled EEM PARAFAC, FT-IR and (1)H NMR approach
This study provides insights into the fluorophoric composition of aqueous brown carbon (BrC(aq)) and chemically-separated humic-like substances (HULIS): neutral HULIS (HULIS-n; at pH = 7) and acidic HULIS (HULIS-a; at pH = 2) on a seasonal and day-night basis in the eastern Indo-Gangetic Plain (IGP), India. A coupled approach including excitation-emission matrix (EEM) fluorescence and parallel factor analysis (PARAFAC)...
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[NMR paper] Unraveling Compositional Study, Chemometric Analysis, and Cell-Based Antioxidant Potential of Selective High Nutraceutical Value Amaranth Cultivars Using a GC-MS and NMR-Based Metabolomics Approach
Unraveling Compositional Study, Chemometric Analysis, and Cell-Based Antioxidant Potential of Selective High Nutraceutical Value Amaranth Cultivars Using a GC-MS and NMR-Based Metabolomics Approach
Amaranthus (family Amaranthaceae) is a potentially nutritious pseudocereal also known as a functional food owing to its high nutritional quality grains especially rich in essential amino acids. Emerging study, however, unambiguously indicates that apart from essential nutrients like protein, other phytochemicals present in amaranth seeds provide excellent health benefits. Squalene is one such...
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12-27-2023 08:40 AM
[NMR paper] A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
Related Articles A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
Magn Reson Med. 2017 Aug 22;:
Authors: Abrami M, Ascenzioni F, Di Domenico EG, Maschio M, Ventura A, Confalonieri M, Di Gioia S, Conese M, Dapas B, Grassi G, Grassi M
Abstract
PURPOSE: Development of a reliable, simple method to monitor lung condition in...
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08-25-2017 04:11 AM
[NMR paper] NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
Biochem Biophys Res Commun. 2015 Dec 1;
Authors: Wu J, Domellöf M, Zivkovic AM, Larsson G, Öhman A, Nording ML
Abstract
Low-molecular-weight metabolites in human milk are gaining increasing interest in studies of infant nutrition. In the present study, the milk metabolome...
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12-15-2015 08:09 PM
[NMR paper] Solid-state NMR in the analysis of drugs and naturally occurring materials.
Solid-state NMR in the analysis of drugs and naturally occurring materials.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Solid-state NMR in the analysis of drugs and naturally occurring materials.
J Pharm Biomed Anal. 2013 Oct 14;
Authors: Paradowska K, Wawer I
Abstract
This article presents some of the solid-state NMR (SSNMR) techniques used in the pharmaceutical and biomedical research. Solid-state magic angle spinning (MAS) NMR provides...
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[NMR paper] Gadolinium leakage into subarachnoid space and cystic metastases.
Gadolinium leakage into subarachnoid space and cystic metastases.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.dirjournal.org-images-pubmed.jpg http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.dirjournal.org-images-pubmed.jpg Related Articles Gadolinium leakage into subarachnoid space and cystic metastases.
Diagn Interv Radiol. 2013 Jan 21;
Authors: Yildiz AE, Atli E, Oguz KK
Abstract
Subarachnoid space (SAS) and cystic metastatic lesions of brain parenchyma appear hypointense on fluid-attenuated...
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[NMR paper] Solid state NMR sequential resonance assignments and conformational analysis of the 2
Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh.
Related Articles Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh.
J Biomol NMR. 2003 Dec;27(4):323-39
Authors: Böckmann A, Lange A, Galinier A, Luca S, Giraud N, Juy M, Heise H, Montserret R, Penin F, Baldus M
Solid state NMR sample preparation and resonance assignments of the U- 2x10.4 kDa dimeric form...
Solid-state NMR compositional analysis of sputum from people with cystic fibrosis
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