Publication date: August 2014 Source:Progress in Nuclear Magnetic Resonance Spectroscopy, Volume 81
Author(s): Konstantin L. Ivanov , Andrey N. Pravdivtsev , Alexandra V. Yurkovskaya , Hans-Martin Vieth , Robert Kaptein
Nuclear spin hyperpolarization is an important resource for increasing the sensitivity of NMR spectroscopy and MRI. Signal enhancements can be as large as 3–4 orders of magnitude. In hyperpolarization experiments, it is often desirable to transfer the initial polarization to other nuclei of choice, either protons or insensitive nuclei such as 13C and 15N. This situation arises primarily in Chemically Induced Dynamic Nuclear Polarization (CIDNP), Para-Hydrogen Induced Polarization (PHIP), and the related Signal Amplification By Reversible Exchange (SABRE). Here we review the recent literature on polarization transfer mechanisms, in particular focusing on the role of Level Anti-Crossings (LACs) therein. So-called “spontaneous” polarization transfer may occur both at low and high magnetic fields. In addition, transfer of spin polarization can be accomplished by using especially designed pulse sequences. It is now clear that at low field spontaneous polarization transfer is primarily due to coherent spin-state mixing under strong coupling conditions. However, thus far the important role of LACs in this process has not received much attention. At high magnetic field, polarization may be transferred by cross-relaxation effects. Another promising high-field technique is to generate the strong coupling condition by spin locking using strong radio-frequency fields. Here, an analysis of polarization transfer in terms of LACs in the rotating frame is very useful to predict which spin orders are transferred depending on the strength and frequency of the B 1 field. Finally, we will examine the role of strong coupling and LACs in magnetic-field dependent nuclear spin relaxation and the related topic of long-lived spin-states. Graphical abstract
Exploiting level anti-crossings (LACs) in the rotating frame for transferring spin hyperpolarization
From The DNP-NMR Blog:
Exploiting level anti-crossings (LACs) in the rotating frame for transferring spin hyperpolarization
Pravdivtsev, A.N., et al., Exploiting level anti-crossings (LACs) in the rotating frame for transferring spin hyperpolarization. Phys Chem Chem Phys, 2014. 16(35): p. 18707-19.
http://www.ncbi.nlm.nih.gov/pubmed/24870026
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08-20-2014 02:06 PM
The role of level anti-crossings in nuclear spin hyperpolarization
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The role of level anti-crossings in nuclear spin hyperpolarization
Ivanov, K.L., et al., The role of level anti-crossings in nuclear spin hyperpolarization. Prog. NMR. Spec., 2014. 81(0): p. 1-36.
http://www.sciencedirect.com/science/article/pii/S0079656514000454
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08-18-2014 10:14 PM
Spin dynamic simulations of solid effect DNP: the role of the relaxation superoperator
From The DNP-NMR Blog:
Spin dynamic simulations of solid effect DNP: the role of the relaxation superoperator
Karabanov, A., G. Kwiatkowski, and W. Köckenberger, Spin dynamic simulations of solid effect DNP: the role of the relaxation superoperator. Mol. Phys., 2014: p. 1-17.
http://dx.doi.org/10.1080/00268976.2014.884287
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07-09-2014 05:07 PM
Role of Electron Spin Dynamics on Solid-State Dynamic Nuclear Polarization Performance
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Role of Electron Spin Dynamics on Solid-State Dynamic Nuclear Polarization Performance
Siaw, T.A., et al., Role of Electron Spin Dynamics on Solid-State Dynamic Nuclear Polarization Performance. Phys. Chem. Chem. Phys., 2014.
http://dx.doi.org/10.1039/C4CP02013H
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06-20-2014 08:14 PM
Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments
From The DNP-NMR Blog:
Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments
Pravdivtsev, A.N., et al., Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments. ChemPhysChem, 2013. 14(14): p. 3327-3331.
http://www.ncbi.nlm.nih.gov/pubmed/23959909
Level anti-crossings in ParaHydrogen Induced Polarization experiments with Cs-symmetric molecules
From The DNP-NMR Blog:
Level anti-crossings in ParaHydrogen Induced Polarization experiments with Cs-symmetric molecules
Buljubasich, L., et al., Level anti-crossings in ParaHydrogen Induced Polarization experiments with Cs-symmetric molecules. J Magn Reson, 2012. 219(0): p. 33-40.
http://www.ncbi.nlm.nih.gov/pubmed/22595295
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11-21-2013 01:14 AM
Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G(*) apolipoprotein J peptide using solution NMR.
Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G(*) apolipoprotein J peptide using solution NMR.
Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G(*) apolipoprotein J peptide using solution NMR.
Biochim Biophys Acta. 2011 Jan;1808(1):498-507
Authors: Mishra VK, Palgunachari MN, Hudson JS, Shin R, Keenum TD, Krishna NR, Anantharamaiah GM
The surprising observation that a 10-residue class G(?) peptide from apolipoprotein J, apoJ, possesses...
The role of level anti-crossings in nuclear spin hyperpolarization
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