[NMR paper] Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts.
Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts.
Related Articles Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts.
J Mol Biol. 2014 Feb 11;
Authors: Kukic P, Camilloni C, Cavalli A, Vendruscolo M
Abstract
Many protein molecules are formed by two or more domains whose structures and dynamics are closely related to their biological functions. It is thus important to develop methods to...
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Interdomain Dynamics Explored by Paramagnetic NMR
Interdomain Dynamics Explored by Paramagnetic NMR
Luigi Russo, Mitcheell Maestre-Martinez, Sebastian Wolff, Stefan Becker and Christian Griesinger
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja408143f/aop/images/medium/ja-2013-08143f_0006.gif
Journal of the American Chemical Society
DOI: 10.1021/ja408143f
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/ShdDw1zwpdY
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[NMR paper] The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged he
The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy.
Related Articles The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy.
Nucleic Acids Res. 2003 Dec 15;31(24):7199-207
Authors: Ono K, Kusano O, Shimotakahara S, Shimizu M, Yamazaki T, Shindo H
Hho1p is assumed to serve as a linker histone in Saccharomyces cerevisiae and, notably, it possesses two putative globular...
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[NMR paper] Second-site NMR screening and linker design.
Second-site NMR screening and linker design.
Related Articles Second-site NMR screening and linker design.
Curr Top Med Chem. 2003;3(1):69-80
Authors: Jahnke W, Flörsheimer A, Blommers MJ, Paris CG, Heim J, Nalin CM, Perez LB
One of the prime merits of NMR as a tool for lead finding in drug discovery research is its sensitivity and robustness to detect weak protein-ligand interactions. This sensitivity allows to build up ligands for a given target in a modular way, by a fragment-based approach. In this approach, two ligands are seperately...
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[NMR paper] NMR structure of activated CheY.
NMR structure of activated CheY.
Related Articles NMR structure of activated CheY.
J Mol Biol. 2000 Mar 31;297(3):543-51
Authors: Cho HS, Lee SY, Yan D, Pan X, Parkinson JS, Kustu S, Wemmer DE, Pelton JG
The CheY protein is the response regulator in bacterial chemotaxis. Phosphorylation of a conserved aspartyl residue induces structural changes that convert the protein from an inactive to an active state. The short half-life of the aspartyl-phosphate has precluded detailed structural analysis of the active protein. Persistent activation of...
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11-18-2010 09:15 PM
[NMR paper] Direct determination of changes of interdomain orientation on ligation: use of the or
Direct determination of changes of interdomain orientation on ligation: use of the orientational dependence of 15N NMR relaxation in Abl SH(32).
Related Articles Direct determination of changes of interdomain orientation on ligation: use of the orientational dependence of 15N NMR relaxation in Abl SH(32).
Biochemistry. 1999 Aug 10;38(32):10225-30
Authors: Fushman D, Xu R, Cowburn D
The relative orientation and motions of domains within many proteins are key to the control of multivalent recognition, or the assembly of protein-based cellular...
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[NMR paper] Import, processing, and two-dimensional NMR structure of a linker-deleted signal pept
Import, processing, and two-dimensional NMR structure of a linker-deleted signal peptide of rat liver mitochondrial aldehyde dehydrogenase.
Related Articles Import, processing, and two-dimensional NMR structure of a linker-deleted signal peptide of rat liver mitochondrial aldehyde dehydrogenase.
J Biol Chem. 1993 Sep 15;268(26):19906-14
Authors: Thornton K, Wang Y, Weiner H, Gorenstein DG
Previous NMR studies (Karslake, C., Piotto, M. E., Pak, Y. M., Weiner, H., and Gorenstein, D. G. (1990) Biochemistry 29, 9872-9878) had shown that a 22-amino...
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[NMR paper] Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by
Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc-MS.gif Related Articles Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering.
J Biol Chem. 1993 Jun 25;268(18):13089-96
Authors: Bourret RB, Drake SK, Chervitz SA, Simon MI, Falke JJ
The Escherichia coli CheY protein is activated by phosphorylation,...
Role of the Interdomain Linker in RNA-Activated ProteinKinase Activation
Linear Mode
