Related ArticlesThe race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine knot protein. Sequence-specific 1H NMR assignments, secondary structure and global fold of the protein.
FEBS Lett. 1997 Mar 10;404(2-3):153-8
Authors: Vervoort J, van den Hooven HW, Berg A, Vossen P, Vogelsang R, Joosten MH, de Wit PJ
The secondary structure and global fold of the AVR9 elicitor protein of Cladosporium fulvum has been determined by 2D NMR and distance-geometry protocols. The protein consists of three anti-parallel strands forming a rigid region of beta-sheet. On the basis of the NMR-derived parameters and distance geometry calculations, it is evident that the AVR9 protein is structurally very homologuous to carboxy peptidase inhibitor (CPI) of which the X-ray structure is known. The AVR9 protein reveals the presence of a cystine knot, which consists of a ring formed by two disulfide bridges and the interconnecting backbone through which the third disulfide bridge penetrates. This structural motif is found in several small proteins such as proteinase inhibitors, ion channel blockers and growth factors. The implications of the structural relationship between AVR9 and other biologically active proteins are discussed.
[NMR paper] Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-relat
Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity.
Related Articles Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity.
Biochemistry. 2002 Jun 18;41(24):7565-72
Authors: Jackson PJ, McNulty JC, Yang YK, Thompson DA, Chai B, Gantz I, Barsh GS, Millhauser GL
The agouti-related protein (AGRP) is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. The...
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[NMR paper] The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine
The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine knot protein. Sequence-specific 1H NMR assignments, secondary structure and global fold of the protein.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine knot protein. Sequence-specific 1H NMR assignments, secondary structure and global fold of the protein.
FEBS Lett. 1997 Mar 10;404(2-3):153-8
Authors: Vervoort...
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[NMR paper] Determination of the NMR solution structure of a specific DNA complex of the Myb DNA-
Determination of the NMR solution structure of a specific DNA complex of the Myb DNA-binding domain.
Related Articles Determination of the NMR solution structure of a specific DNA complex of the Myb DNA-binding domain.
J Biomol NMR. 1995 Nov;6(3):294-305
Authors: Morikawa S, Ogata K, Sekikawa A, Sarai A, Ishii S, Nishimura Y, Nakamura H
The solution structure of a specific DNA complex of the minimum DNA-binding domain of the mouse c-Myb protein was determined by distance geometry calculations using a set of 1732 nuclear Overhauser enhancement...
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[NMR paper] 1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of tr
1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles 1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.
Eur J Biochem. 1999 Jun;262(2):586-94
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Analysis of and chemical shifts of cysteine and cystine residues in proteins: a quant
Abstract Cysteines possess a unique property among the 20 naturally occurring amino acids: it can be present in proteins in either the reduced or oxidized form, and can regulate the activity of some proteins. Consequently, to augment our previous treatment of the other types of residues, the
13\textC\upalpha and
13\textC\upbeta chemical shifts of 837 cysteines in disulfide-bonded cystine from a set of seven non-redundant proteins, determined by X-ray crystallography and NMR spectroscopy, were computed at the DFT level of theory. Our results indicate that the errors between observed...
The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine
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