[NMR paper] Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness.
Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness.
Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness.
Chem Biol Drug Des. 2016 Jun 22;
Authors: Stefanachi A, Mangiatordi GF, Tardia P, Alberga D, Leonetti F, Niso M, Colabufo NA, Adamo C, Nicolotti O, Cellamare S
Abstract
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06-23-2016 10:34 AM
[NMR paper] Solid-state NMR sequential assignments of the N-terminal domain of HpDnaB helicase.
Solid-state NMR sequential assignments of the N-terminal domain of HpDnaB helicase.
Related Articles Solid-state NMR sequential assignments of the N-terminal domain of HpDnaB helicase.
Biomol NMR Assign. 2015 Aug 18;
Authors: Wiegand T, Gardiennet C, Ravotti F, Bazin A, Kunert B, Lacabanne D, Cadalbert R, Güntert P, Terradot L, Böckmann A, Meier BH
Abstract
We present solid-state NMR assignments of the N-terminal domain of the DnaB helicase from Helicobacter pylori (153 residues) in its microcrystalline form. We use a sequential...
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08-19-2015 03:24 PM
[NMR paper] Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets.
Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets.
Related Articles Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets.
ACS Med Chem Lett. 2010 Sep 9;1(6):295-9
Authors: Swann SL, Song D, Sun C, Hajduk PJ, Petros AM
Abstract
NMR spectroscopy has enjoyed widespread success as a method for screening protein targets, especially in the area of fragment-based drug discovery. However, current methods for NMR-based screening all suffer certain limitations. Two-dimensional methods...
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06-07-2014 07:12 PM
[NMR paper] NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans.
NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans.
FEBS Lett. 2013 Aug 19;587(16):2635-42
Authors: Liu S, Zhang W, Gao Z, Ming Q, Hou H, Lan W, Wu H, Cao C, Dong Y
Abstract
The RecQ helicase from Deinococcus radiodurans (DrRecQ) distinguishes from other...
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10-24-2013 08:45 PM
[NMR paper] NMR Mapping of PCNA Interaction with Translesion Synthesis DNA Polymerase Rev1 Mediated by Rev1-BRCT Domain.
NMR Mapping of PCNA Interaction with Translesion Synthesis DNA Polymerase Rev1 Mediated by Rev1-BRCT Domain.
Related Articles NMR Mapping of PCNA Interaction with Translesion Synthesis DNA Polymerase Rev1 Mediated by Rev1-BRCT Domain.
J Mol Biol. 2013 Jun 6;
Authors: Pustovalova Y, Maciejewski MW, Korzhnev DM
Abstract
Rev1 is a Y-family translesion synthesis (TLS) DNA polymerase involved in bypass replication across sites of DNA damage and postreplicational gap filling. In the process of TLS high-fidelity replicative DNA polymerases...
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06-12-2013 11:42 AM
[NMR paper] Expression, purification, crystallization, and NMR studies of the helicase interactio
Expression, purification, crystallization, and NMR studies of the helicase interaction domain of Escherichia coli DnaG primase.
Related Articles Expression, purification, crystallization, and NMR studies of the helicase interaction domain of Escherichia coli DnaG primase.
Protein Expr Purif. 2004 Feb;33(2):304-10
Authors: Loscha K, Oakley AJ, Bancia B, Schaeffer PM, Prosselkov P, Otting G, Wilce MC, Dixon NE
In Escherichia coli, the DnaG primase is the RNA polymerase that synthesizes RNA primers at replication forks. It is composed of three...
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11-24-2010 09:25 PM
[NMR paper] Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectrosco
Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.
Biochem Biophys Res Commun. 1997 Feb 3;231(1):126-30
Authors: Miles CS, Weigelt J, Stamford NP, Dammerova N, Otting G, Dixon NE
Two separate N-terminal fragments of the 470-amino-acid Escherichia coli DnaB helicase, comprising residues 1-142 and...
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08-22-2010 03:31 PM
[NMR paper] Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectrosco
Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.
Biochem Biophys Res Commun. 1997 Feb 3;231(1):126-30
Authors: Miles CS, Weigelt J, Stamford NP, Dammerova N, Otting G, Dixon NE
Two separate N-terminal fragments of the 470-amino-acid Escherichia coli DnaB helicase, comprising residues 1-142 and...