[NMR paper] Investigating liquid-liquid phase separation of a monoclonal antibody using solution-state NMR spectroscopy: effect of Arg·Glu and Arg·HCl.
Investigating liquid-liquid phase separation of a monoclonal antibody using solution-state NMR spectroscopy: effect of Arg·Glu and Arg·HCl.
Investigating liquid-liquid phase separation of a monoclonal antibody using solution-state NMR spectroscopy: effect of Arg·Glu and Arg·HCl.
Mol Pharm. 2017 Jun 14;:
Authors: Kheddo P, Bramham JE, Dearman RJ, Uddin S, van der Walle CF, Golovanov AP
Abstract
Liquid-liquid phase separation (LLPS) of monoclonal antibody (mAb) formulations involves spontaneous separation into dense...
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06-15-2017 03:37 PM
[NMR paper] Reconstruction of non-uniformly sampled five-dimensional NMR spectra by signal separation algorithm.
Reconstruction of non-uniformly sampled five-dimensional NMR spectra by signal separation algorithm.
Related Articles Reconstruction of non-uniformly sampled five-dimensional NMR spectra by signal separation algorithm.
J Biomol NMR. 2017 Feb 28;:
Authors: Kosi?ski K, Stanek J, Górka MJ, ?erko S, Ko?mi?ski W
Abstract
A method for five-dimensional spectral reconstruction of non-uniformly sampled NMR data sets is proposed. It is derived from the previously published signal separation algorithm, with major alterations to avoid...
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03-01-2017 05:04 PM
Reconstruction of non-uniformly sampled five-dimensional NMR spectra by signal separation algorithm
Reconstruction of non-uniformly sampled five-dimensional NMR spectra by signal separation algorithm
Abstract
A method for five-dimensional spectral reconstruction of non-uniformly sampled NMR data sets is proposed. It is derived from the previously published signal separation algorithm, with major alterations to avoid unfeasible processing of an entire five-dimensional spectrum. The proposed method allows credible reconstruction of spectra from as little as a few hundred data points and enables sensitive resonance detection in experiments with a high...
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03-01-2017 04:13 AM
SolutionNMR Experiment for Measurement of 15N–1H Residual Dipolar Couplings in Large Proteinsand Supramolecular Complexes
SolutionNMR Experiment for Measurement of 15N–1H Residual Dipolar Couplings in Large Proteinsand Supramolecular Complexes
Alexander Eletsky, Surya V.S.R.K. Pulavarti, Victor Beaumont, Paul Gollnick and Thomas Szyperski
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.5b07010/20150827/images/medium/ja-2015-07010d_0003.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.5b07010
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/Hmt-BNlZ_qs
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08-28-2015 12:45 AM
Separation anxiety: Magnetic metal recycling
Separation anxiety: Magnetic metal recycling
http://www.spectroscopynow.com/common/images/thumbnails/14de2b98b56.jpgRare earth magnets are widely used in a range of gadgets, instrumentation and even toys but recycling the mixtures of metals from which the magnets are formed is difficult. Now, research published in the journal Angewandte Chemie offers a novel approach to the isolation of neodymium and dysprosium from dismantled magnets. The technique could ward off a future shortage of these metals.
Read the rest at Spectroscopynow.com
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06-15-2015 02:38 AM
Phosphate–WaterInterplay Tunes Amorphous CalciumCarbonate Metastability: Spontaneous Phase Separation and Crystallizationvs Stabilization Viewed by Solid State NMR
Phosphate–WaterInterplay Tunes Amorphous CalciumCarbonate Metastability: Spontaneous Phase Separation and Crystallizationvs Stabilization Viewed by Solid State NMR
Shifi Kababya, Assaf Gal, Keren Kahil, Steve Weiner, Lia Addadi and Asher Schmidt
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja511869g/20150105/images/medium/ja-2014-11869g_0007.gif
Journal of the American Chemical Society
DOI: 10.1021/ja511869g
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA...
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01-06-2015 07:59 PM
A review of blind source separation in NMR spectroscopy
A review of blind source separation in NMR spectroscopy
Publication date: August 2014
Source:Progress in Nuclear Magnetic Resonance Spectroscopy, Volume 81</br>
Author(s): Ichrak Toumi , Stefano Caldarelli , Bruno Torrésani</br>
Fourier transform is the data processing naturally associated to most NMR experiments. Notable exceptions are Pulse Field Gradient and relaxation analysis, the structure of which is only partially suitable for FT. With the revamp of NMR of complex mixtures, fueled by analytical challenges such as metabolomics, alternative and more apt...
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08-24-2014 04:05 PM
[NMR paper] A solid-state NMR study of molecular mobility and phase separation in co-spray-dried
A solid-state NMR study of molecular mobility and phase separation in co-spray-dried protein-sugar particles.
Related Articles A solid-state NMR study of molecular mobility and phase separation in co-spray-dried protein-sugar particles.
Eur J Pharm Sci. 2005 May;25(1):105-12
Authors: Suihko EJ, Forbes RT, Apperley DC
Molecular mobility and physical form of co-spray-dried sugar-lysozyme formulations were evaluated. Co-spray-dried trehalose:lysozyme and sucrose:lysozyme formulations in 1:9, 1:1 and 9:1 ratios (w:w) were stored at 0% RH and 75%...
Phase Separation Behavior of Supercharged Proteinsand Polyelectrolytes
Linear Mode
