Related ArticlesPara-hydrogen perspectives in hyperpolarized NMR.
J Magn Reson. 2013 Oct;235:130-42
Authors: Glöggler S, Colell J, Appelt S
Abstract
The first instance of para-hydrogen induced polarization (PHIP) in an NMR experiment was serendipitously observed in the 1980s while investigating a hydrogenation reaction (Seldler et al., 1983; Bowers and Weitekamp, 1986, 1987; Eisenschmid et al., 1987) [1-4]. Remarkably a theoretical investigation of the applicability of para-hydrogen as a hyperpolarization agent was being performed in the 1980's thereby quickly providing a theoretical basis for the PHIP-effect (Bowers and Weitekamp, 1986) [2]. The discovery of signal amplification by a non-hydrogenating interaction with para-hydrogen has recently extended the interest to exploit the PHIP effect, as it enables investigation of compounds without structural alteration while retaining the advantages of spectroscopy with hyperpolarized compounds [5]. In this article we will place more emphasis of the future applications of the method while only briefly discussing the efforts that have been made in the understanding of the phenomenon and the development of the method so far.
Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments
From The DNP-NMR Blog:
Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments
Pravdivtsev, A.N., et al., Level Anti-Crossings are a Key Factor for Understanding para-Hydrogen-Induced Hyperpolarization in SABRE Experiments. ChemPhysChem, 2013. 14(14): p. 3327-3331.
http://www.ncbi.nlm.nih.gov/pubmed/23959909
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04-16-2014 11:09 PM
Evidence for Coherent Transfer of para-Hydrogen-Induced Polarization at Low Magnetic Fields
From The DNP-NMR Blog:
Evidence for Coherent Transfer of para-Hydrogen-Induced Polarization at Low Magnetic Fields
Kiryutin, A.S., et al., Evidence for Coherent Transfer of para-Hydrogen-Induced Polarization at Low Magnetic Fields. The Journal of Physical Chemistry Letters, 2013. 4(15): p. 2514-2519.
http://dx.doi.org/10.1021/jz401210m
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11-21-2013 01:14 AM
[NMR paper] Use of H/D isotope effects to gather information about hydrogen bonding and hydrogen exchange rates
Use of H/D isotope effects to gather information about hydrogen bonding and hydrogen exchange rates
Publication date: Available online 11 October 2013
Source:Journal of Magnetic Resonance</br>
Author(s): Mitsuhiro Takeda , Yohei Miyanoiri , Tsutomu Terauchi , Chin-Jiun Yang , Masatsune Kainosho</br>
Polar side-chains in proteins play important roles in formingand maintaining three-dimensional structures, and thus participate invarious biological functions. Until recently, most protein NMR studieshave focused onthe non-exchangeable protons of amino acid...
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10-11-2013 10:43 AM
Perspectives of hyperpolarized noble gas MRI beyond 3He
From the The DNP-NMR Blog:
Perspectives of hyperpolarized noble gas MRI beyond 3He
Lilburn, D.M.L., G.E. Pavlovskaya, and T. Meersmann, Perspectives of hyperpolarized noble gas MRI beyond 3He. J. Magn. Reson., 2013. 229(0): p. 173-186.
http://www.sciencedirect.com/science/article/pii/S1090780712003588
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04-15-2013 08:52 AM
High Resolution Para-Hydrogen Induced Polarization in Inhomogeneous Magnetic Fields
From the The DNP-NMR Blog:
High Resolution Para-Hydrogen Induced Polarization in Inhomogeneous Magnetic Fields
Buljubasich, L., et al., High Resolution Para-Hydrogen Induced Polarization in Inhomogeneous Magnetic Fields. J. Magn. Reson., 2013(0).
http://dx.doi.org/10.1016/j.jmr.2013.02.008
Para-hydrogen perspectives in hyperpolarized NMR.
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