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Biochem Cell Biol. 1997;75(2):163-9
Authors: Brockbank RL, Vogel HJ
The proton and carbon-13 NMR resonances for the 13-residue synthetic RRsrc peptide were completely assigned using two-dimensional NMR spectroscopy. This peptide contains a tyrosine in position 9 that can be phosphorylated by many tyrosine protein kinases. On the basis of observed nuclear Overhauser enhancements and alpha-proton and alpha-carbon chemical shifts, the peptide appears to interconvert between extended and nascent helical structures. The helical conformation found in aqueous solution is compared with the corresponding structure calculated for the tyrosine 416 site of pp60src by homology modeling to the cAMP-dependent protein kinase (PKA) and also to the conformation modelled after the bound form of a PKA-inhibitor peptide.
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J Pept Res. 1997 Mar;49(3):210-20
Authors: Padilla A, Hauer JA, Tsigelny I, Parello J, Taylor SS
Peptides derived from the inhibitor of cAMP-dependent protein kinase. PKI, have been studied by 2D 1H NMR techniques. These include the inhibitor...
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[NMR paper] NMR studies of the RRsrc peptide, a tyrosine kinase substrate.
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http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.nrc-cnrc.gc.ca-cisti-journals-rp-gifs-PubMed_logo_e.gif Related Articles NMR studies of the RRsrc peptide, a tyrosine kinase substrate.
Biochem Cell Biol. 1997;75(2):163-9
Authors: Brockbank RL, Vogel HJ
The proton and carbon-13 NMR resonances for the 13-residue synthetic RRsrc peptide were completely assigned using two-dimensional NMR spectroscopy. This peptide contains a tyrosine in position 9 that can be phosphorylated...
nmrlearner
Journal club
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08-22-2010 03:31 PM
[NMR paper] Solution structure of synthetic peptide inhibitor and substrate of cAMP-dependent pro
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J Pept Res. 1997 Mar;49(3):210-20
Authors: Padilla A, Hauer JA, Tsigelny I, Parello J, Taylor SS
Peptides derived from the inhibitor of cAMP-dependent protein kinase. PKI, have been studied by 2D 1H NMR techniques. These include the inhibitor...
NMR studies of the RRsrc peptide, a tyrosine kinase substrate.
Linear Mode
