Related ArticlesNMR spectroscopic characterization of a model RNA duplex reflecting the core sequence of hammerhead ribozymes.
Nucleosides Nucleotides Nucleic Acids. 2018 Jun 28;:1-14
Authors: Hattori Y, Yamanaka D, Morioka S, Yamaguchi T, Tomonari H, Kojima C, Tanaka Y
Abstract
Hammerhead ribozymes are a model system for studying molecular mechanism of RNA catalysis. Physicochemical data-driven mechanistic studies are an indispensable step towards understanding the catalysis of hammerhead ribozymes. Here we characterized a model RNA duplex with catalytically important sheared-type G12-A9 base pair and A9-G10.1 metal ion-binding motif in hammerhead ribozymes. By using high magnetic field NMR, all base proton signals, including catalytic residues, were unambiguously assigned. We further characterized structural features of this RNA molecule and found that it reflects the structural features of the A9-G10.1 motif of hammerhead ribozymes. Therefore, this RNA molecule is suitable for extracting an intrinsic physicochemical properties of catalytically important residues.
PMID: 29953330 [PubMed - as supplied by publisher]
[NMR paper] Exploring a DNA Sequence for the Three-Dimensional Structure Determination of a Silver(I)-Mediated C-C Base Pair in a DNA Duplex By (1)H NMR Spectroscopy.
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Nucleosides Nucleotides Nucleic Acids. 2015 Nov 17;:1-24
Authors: Dairaku T, Furuita K, Sato H, Kondo Y, Kojima C, Ono A, Tanaka Y
Abstract
Recently, we discovered novel silver(I)-mediated...
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[NMR paper] NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors.
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http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary_FullTextOnline_120x27.gif Related Articles NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors.
Magn Reson Chem. 2014 Aug;52(8):470-3
Authors: Rubio-Ruiz B, Espinosa A, Entrena Guadix A, Conejo-García A
PMID: 24916016
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NMR spectroscopic characterization of ms protein folding
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Sequence-Dependent Enrichment of a Model Phosphopeptide: A Combined MALDI-TOF and NMR Study.
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Anal Chem. 2011 Mar 23;
Authors: Lucre?ce M, Emmanuelle S, Fabienne B, Sandrine S, Olivier L, Ge?rard B
The goal of this study was to detect and quantify by MALDI-TOF MS the phosphorylation of a peptide containing the recognition motif of the Protein Kinase C (PKC). Such model peptide can be used as a phosphorylation probe to follow intracellular...
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03-25-2011 06:34 PM
[NMR paper] Phosphorylated amino acids: model compounds for solid-state 31P NMR spectroscopic stu
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Biochim Biophys Acta. 2002 Aug 31;1564(2):317-24
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J Inorg Biochem. 1990 Jun;39(2):149-59
Authors: Banci L, Bertini I, Caliceti P, Monsù Scolaro L, Schiavon O, Veronese FM
Spectroscopic methods have been employed in order to understand the molecular basis of the decrease in enzymatic activity of the antiinflammatory enzyme...
NMR spectroscopic characterization of a model RNA duplex reflecting the core sequence of hammerhead ribozymes.
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