The E. coli ? clamp loader is a pentameric complex of ?, ?' and three ? subunits that opens and loads ?-clamp proteins onto DNA in an ATP-dependent process essential for efficient DNA replication. ATP binding to the ? subunits promotes conformational changes that enable the clamp loader to bind and open the ring-shaped ?-clamp homodimer. Here we report the nearly complete backbone and side-chain ¹H, ^(13)C and ^(15)N NMR resonance assignments of the 242-residue truncated ? subunit of the clamp...
Neutron Crystallography Detects Differences in ProteinDynamics: Structure of the PKG II Cyclic Nucleotide Binding Domainin Complex with an Activator
Neutron Crystallography Detects Differences in ProteinDynamics: Structure of the PKG II Cyclic Nucleotide Binding Domainin Complex with an Activator
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Biochemistry
DOI: 10.1021/acs.biochem.8b00010
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[NMR paper] NMR resonance assignments for the N-terminal domain of the ? subunit of the E. coli ? clamp loader complex.
NMR resonance assignments for the N-terminal domain of the ? subunit of the E. coli ? clamp loader complex.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles NMR resonance assignments for the N-terminal domain of the ? subunit of the E. coli ? clamp loader complex.
Biomol NMR Assign. 2017 Mar 06;:
Authors: Alyami EM, Rizzo AA, Beuning PJ, Korzhnev DM
Abstract
The ?-clamp protein and the ? clamp loader complex are essential...
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03-09-2017 12:11 AM
[NMR paper] Escherichia coli topoisomerase IV E subunit and an inhibitor binding mode revealed by NMR spectroscopy.
Escherichia coli topoisomerase IV E subunit and an inhibitor binding mode revealed by NMR spectroscopy.
Escherichia coli topoisomerase IV E subunit and an inhibitor binding mode revealed by NMR spectroscopy.
J Biol Chem. 2016 Jun 30;
Authors: Li Y, Wong YL, Ng FM, Liu B, Wong YX, Poh ZY, Liu S, Then SW, Lee MY, Ng HQ, Huang Q, Hung AW, Cherian J, Hill J, Keller TH, Kang C
Abstract
Bacterial topoisomerases are attractive antibacterial drug targets due to their importance in bacterial growth and low homology with other human...
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07-02-2016 07:23 PM
[NMR paper] NMR backbone resonance assignments of the N, P domains of CopA, a copper-transporting ATPase, in the apo and ligand bound states.
NMR backbone resonance assignments of the N, P domains of CopA, a copper-transporting ATPase, in the apo and ligand bound states.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles NMR backbone resonance assignments of the N, P domains of CopA, a copper-transporting ATPase, in the apo and ligand bound states.
Biomol NMR Assign. 2015 Apr;9(1):129-33
Authors: Meng D, Bruschweiler-Li L, Zhang F, Brüschweiler R
Abstract
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[NMR paper] NMR study of nucleotide-induced changes in the nucleotide binding domain of Thermus t
NMR study of nucleotide-induced changes in the nucleotide binding domain of Thermus thermophilus Hsp70 chaperone DnaK: implications for the allosteric mechanism.
Related Articles NMR study of nucleotide-induced changes in the nucleotide binding domain of Thermus thermophilus Hsp70 chaperone DnaK: implications for the allosteric mechanism.
J Biol Chem. 2004 Aug 6;279(32):33958-67
Authors: Revington M, Holder TM, Zuiderweg ER
We present an NMR investigation of the nucleotide-dependent conformational properties of a 44-kDa nucleotide binding...
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11-24-2010 09:51 PM
[NMR paper] Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a ro
Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a role for N-terminal residues in tandem binding.
Related Articles Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a role for N-terminal residues in tandem binding.
J Biomol NMR. 1998 Apr;11(3):307-18
Authors: Shan X, Gardner KH, Muhandiram DR, Kay LE, Arrowsmith CH
Deuterium decoupled, triple resonance NMR spectroscopy was used to analyze complexes of 2H, 15N, 13C labelled intact and (des2-7) trp repressor (delta 2-7 trpR) from E....
NMR resonance assignments for the nucleotide binding domains of the E. coli clamp loader complex gamma subunit
Linear Mode
