Signalosomes are high-order protein machineries involved in complex mechanisms controlling regulated immune defense and cell death execution. The immune response is initiated by the recognition of exogeneous or endogenous signals, triggering the signalosome assembly process. The final step of signalosome fate often involves membrane-targeting and activation of pore-forming execution domains, leading to membrane disruption and ultimately cell death. Such cell death-inducing domains have been...
[NMR paper] NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii.
NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii.
Related Articles NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii.
Biomol NMR Assign. 2020 Jun 23;:
Authors: Lin MH, Yu TA, Chang CF, Nishikawa Y, Hsu CH
Abstract
Toxoplasmosis is a systematic protozoan disease caused by a tiny parasite Toxoplasma gondii. The infection can be dangerous for pregnant woman and people with weak immune systems. The secreted protein named TgPDCD5 (Programmed...
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06-25-2020 03:14 PM
Programmed cell death: Solid-state NMR insights
Programmed cell death: Solid-state NMR insights
http://www.spectroscopynow.com/common/images/thumbnails/169b46e7c0b.jpgResearchers from The Netherlands and the USA have used solid-state nuclear magnetic resonance (NMR) spectroscopy to show how the signal induced by the enzyme cytochrome C is more controlled than was originally anticipated. The discovery could have implications for understanding mitochondria and programmed cell death.
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04-02-2019 01:35 AM
[NMR paper] 1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD).
1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD).
1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD).
Biomol NMR Assign. 2018 Jun 05;:
Authors: Baudin A, Guichard A, Collie GW, Rousseau S, Chaignepain S, Hocquellet A, Berbon M, Loquet A, Mackereth C, Guichard G, Odaert B
Abstract
Death...
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06-06-2018 01:42 PM
Preventing Cell Death in Alzheimer's Disease - PsychCentral.com (blog)
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PsychCentral.com (blog)
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Preventing Cell Death in Alzheimer's Disease
PsychCentral.com (blog)
The scientists used a procedure called solid-state nuclear magnetic resonance spectroscopy (solid-state NMR) to identify sites in heat shock proteins called alpha-B-crystallin that attach to the beta-amyloid. But this process is difficult as alpha-B ...
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Preventing Cell Death in Alzheimer's Disease -...
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03-29-2016 04:59 PM
[NMR paper] Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.
Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.
Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.
Biophys J. 2015 Mar 24;108(6):1380-9
Authors: Nygaard R, Romaniuk JA, Rice DM, Cegelski L
Abstract
Gram-positive bacteria surround themselves with a thick cell wall that is essential to cell survival and is a major target of antibiotics. Quantifying alterations in cell-wall composition are crucial to evaluating drug...
NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes
Linear Mode
