This Article presents, for the first time to our knowledge, an untargeted nuclear magnetic resonance (NMR) metabolomic characterization of the polar intracellular metabolic adaptations of human adipose-derived mesenchymal stem cells during osteogenic differentiation. The use of mesenchymal stem cells (MSCs) for bone regeneration is a promising alternative to conventional bone grafts, and untargeted metabolomics may unveil novel metabolic information on the osteogenic differentiation of MSCs,...
[NMR paper] NMR-based metabolomics analysis identifies discriminatory metabolic disturbances in tissue and biofluid samples for progressive prostate cancer.
NMR-based metabolomics analysis identifies discriminatory metabolic disturbances in tissue and biofluid samples for progressive prostate cancer.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles NMR-based metabolomics analysis identifies discriminatory metabolic disturbances in tissue and biofluid samples for progressive prostate cancer.
Clin Chim Acta. 2020 Feb;501:241-251
Authors: Zheng H, Dong B, Ning J, Shao X, Zhao L, Jiang Q, Ji H, Cai A, Xue W, Gao...
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07-30-2020 05:28 PM
[NMR paper] Sensory assessment of fish and chicken protein hydrolysates - evaluation of NMR metabolomics profiling as a new prediction tool.
Sensory assessment of fish and chicken protein hydrolysates - evaluation of NMR metabolomics profiling as a new prediction tool.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Sensory assessment of fish and chicken protein hydrolysates - evaluation of NMR metabolomics profiling as a new prediction tool.
J Agric Food Chem. 2020 Mar 02;:
Authors: Steinsholm S, Oterhals Å, Underhaug J, Mage I, Malmendal A, Aspevik T
Abstract
Nuclear magnetic resonance...
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03-03-2020 11:18 PM
Biomaterials with 'Frankenstein proteins' help heal tissue: Biomaterial that solidifies at body temperature integrates into wounds to help cells grow - Science Daily
Biomaterials with 'Frankenstein proteins' help heal tissue: Biomaterial that solidifies at body temperature integrates into wounds to help cells grow - Science Daily
Biomaterials with 'Frankenstein proteins' help heal tissue: Biomaterial that solidifies at body temperature integrates into wounds to help cells grow Science DailyBiomedical engineers have demonstrated that, by injecting an elastic biomaterial made from ordered and disordered proteins, a scaffold can form that responds ...
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01-07-2019 05:49 AM
Journal Highlight: 1H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness
Journal Highlight: 1H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness
http://www.spectroscopynow.com/common/images/thumbnails/14c5b57869d.jpgMetabolite profiles of 42 glioblastoma stem-like cell lines were screened with 1H NMR spectroscopy and compared with human neural progenitor cells from human adult olfactory bulb and from the developing human brain.
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03-30-2015 06:04 PM
[NMR paper] (1) H NMR detects different metabolic profiles in glioblastoma stem-like cells.
(1) H NMR detects different metabolic profiles in glioblastoma stem-like cells.
Related Articles (1) H NMR detects different metabolic profiles in glioblastoma stem-like cells.
NMR Biomed. 2013 Oct 21;
Authors: Guidoni L, Ricci-Vitiani L, Rosi A, Palma A, Grande S, Luciani AM, Pelacchi F, di Martino S, Colosimo C, Biffoni M, De Maria R, Pallini R, Viti V
Abstract
The metabolic profiles of glioblastoma stem-like cells (GSCs) growing in neurospheres were examined by (1) H NMR spectroscopy. Spectra of two GSC lines, labelled 1 and 83, from...
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10-23-2013 03:49 AM
NMR-based metabolomics of mammalian cell and tissue cultures
NMR-based metabolomics of mammalian cell and tissue cultures
Abstract NMR spectroscopy was used to evaluate growth media and the cellular metabolome in two systems of interest to biomedical research. The first of these was a Chinese hamster ovary cell line engineered to express a recombinant protein. Here, NMR spectroscopy and a quantum mechanical total line shape analysis were utilized to quantify 30 metabolites such as amino acids, Krebs cycle intermediates, activated sugars, cofactors, and others in both media and cell extracts. The impact of bioreactor scale and addition of...
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03-09-2011 04:19 AM
NMR-based metabolomics of mammalian cell and tissue cultures.
NMR-based metabolomics of mammalian cell and tissue cultures.
NMR-based metabolomics of mammalian cell and tissue cultures.
J Biomol NMR. 2011 Mar 4;
Authors: Aranibar N, Borys M, Mackin NA, Ly V, Abu-Absi N, Abu-Absi S, Niemitz M, Schilling B, Li ZJ, Brock B, Russell RJ, Tymiak A, Reily MD
NMR spectroscopy was used to evaluate growth media and the cellular metabolome in two systems of interest to biomedical research. The first of these was a Chinese hamster ovary cell line engineered to express a recombinant protein. Here, NMR spectroscopy and a...
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03-05-2011 01:02 PM
Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR.
Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR.
Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR.
Methods Mol Biol. 2011;691:205-25
Authors: Baverel G, Renault S, Faiz H, El Hage M, Gauthier C, Duplany A, Ferrier B, Martin G
Numerous xenobiotics are toxic to human and animal cells by interacting with their metabolism, but the precise metabolic step affected and the biochemical mechanism behind such a...
NMR Metabolomics Assessment of Osteogenic Differentiation of Adipose-Tissue-Derived Mesenchymal Stem Cells
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