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NMR metabolomic modelling of age and lifespan: a multi-cohort analysis
NMR metabolomic modelling of age and lifespan: a multi-cohort analysis
Metabolomic age models have been proposed for the study of biological aging, however they have not been widely validated. We aimed to assess the performance of newly developed and existing nuclear magnetic resonance spectroscopy (NMR) metabolomic age models for prediction of chronological age (CA), mortality, and age-related disease. 98 metabolic variables were measured in blood from nine UK and Finnish cohort studies (N ? 31,000 individuals, age range 24-86 years). We used non-linear and... More... |
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