[NMR paper] NMR-based identification of the major bioactive molecules from an Italian cultivar of Lycium barbarum.

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NMR-based identification of the major bioactive molecules from an Italian cultivar of Lycium barbarum.

Related Articles NMR-based identification of the major bioactive molecules from an Italian cultivar of Lycium barbarum.

Phytochemistry. 2017 Dec;144:52-57

Authors: Lopatriello A, Previtera R, Pace S, Werner M, Rubino L, Werz O, Taglialatela-Scafati O, Forino M

Abstract
Lycium barbarum (Solanaceae), long known to the traditional Chinese medicine because of its many health-promoting effects, has of late spread widely across the Western hemisphere, mainly on account of the nutritional richness in vitamins, minerals and antioxidant metabolites of its fruits. Data on bioactive metabolites from fruits and leaves, which are commonly consumed in soups and salads, are scarce and sometimes even contradictory. By means of NMR, the present study identified the specialised products contained in an Italian cultivar of L.*barbarum. Kaempeferol, caffeic acid, 3,4,5-trihydroxycinnamic acid and 5-hydroxyferulic acid were found in fresh fruits; rutin and chlorogenic acid were detected in leaves and flowers; also, a previously undescribed N,N-dicaffeoylspermidine derivative was identified in flowers, while N-feruloyltyramine derivatives, for which interesting anti-inflammatory properties have been reported, turned out to be the major bioactive molecules in stems. The plethora of the detected bioactive molecules amplifies the nutraceutical value of berries and leaves and prompts the exploitation of L.*barbarum flowers and pruned stems as sources of beneficial compounds.


PMID: 28888145 [PubMed - indexed for MEDLINE]



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