Related ArticlesNew structural and functional insights from in-cell NMR.
Emerg Top Life Sci. 2018 Apr 20;2(1):29-38
Authors: Luchinat E, Banci L
Abstract
In recent years, it has become evident that structural characterization would gain significantly in terms of biological relevance if framed within a cellular context, while still maintaining the atomic resolution. Therefore, major efforts have been devoted to developing Cellular Structural Biology approaches. In this respect, in-cell NMR can provide and has provided relevant contributions to the field, not only to investigate the structural and dynamical properties of macromolecules in solution but, even more relevant, to understand functional processes directly in living cells and the factors that modulate them, such as exogenous molecules, partner proteins, and oxidative stress. In this commentary, we review and discuss some of the main contributions to the understanding of protein structural and functional properties achieved by in-cell NMR.
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling - Science
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling - Science
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling ScienceForkhead-associated (FHA) domains participate in phosphorylation-dependent signaling pathways by binding to phosphothreonine. As part of a signaling ...
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05-09-2019 11:40 PM
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling - Science
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling - Science
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling ScienceForkhead-associated (FHA) domains participate in phosphorylation-dependent signaling pathways by binding to phosphothreonine. As part of a signaling ...
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05-09-2019 05:55 AM
Unique Insights into the Structural and Functional Biology of Membrane Proteins from Solid State NMR Spectroscopy
Unique Insights into the Structural and Functional Biology of Membrane Proteins from Solid State NMR Spectroscopy
Publication date: 2 February 2018
Source:Biophysical Journal, Volume 114, Issue 3, Supplement 1</br>
Author(s): Timothy Cross, Joana Paulino, Huajun Qin, Yiseul Shin, Cristian Escobar, Rongfu Zhang, Joshua Taylor, Yimin Miao, Riqiang Fu, Eduard Chekmenev, Ivan Hung, Zhehong Gan, Petr Gor'kov</br>
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02-07-2018 03:41 PM
[NMR paper] Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.
Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.
Related Articles Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.
Proc Natl Acad Sci U S A. 2016 Jun 13;
Authors: Shu Q, Krezel AM, Cusumano ZT, Pinkner JS, Klein R, Hultgren SJ, Frieden C
Abstract
Curli, consisting primarily of major structural subunit CsgA, are functional amyloids produced on the surface of...
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06-15-2016 11:12 PM
[NMR paper] Cellulose Structural Polymorphism in Plant Primary Cell Walls Investigated by High-Field 2D Solid-State NMR Spectroscopy and Density Functional Theory Calculations.
Cellulose Structural Polymorphism in Plant Primary Cell Walls Investigated by High-Field 2D Solid-State NMR Spectroscopy and Density Functional Theory Calculations.
Cellulose Structural Polymorphism in Plant Primary Cell Walls Investigated by High-Field 2D Solid-State NMR Spectroscopy and Density Functional Theory Calculations.
Biomacromolecules. 2016 May 18;
Authors: Wang T, Yang H, Kubicki JD, Hong M
Abstract
The native cellulose of bacterial, algal, and animal origins has been well studied structurally using X-ray and neutron...
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05-19-2016 10:13 AM
Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional AnalogueContributing to para-Aminosalicylic Acid Resistance
Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional AnalogueContributing to para-Aminosalicylic Acid Resistance
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.5b00993/20160205/images/medium/bi-2015-009933_0008.gif
Biochemistry
DOI: 10.1021/acs.biochem.5b00993
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02-06-2016 03:10 PM
Magic Angle Spinning and Oriented Sample Solid-State NMR Structural Restraints Combine for Influenza A M2 Protein Functional Insights
Magic Angle Spinning and Oriented Sample Solid-State NMR Structural Restraints Combine for Influenza A M2 Protein Functional Insights
Thach V. Can, Mukesh Sharma, Ivan Hung, Peter L. Gor’kov, William W. Brey and Timothy A. Cross
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja3004039/aop/images/medium/ja-2012-004039_0004.gif
Journal of the American Chemical Society
DOI: 10.1021/ja3004039
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http://feeds.feedburner.com/~r/acs/jacsat/~4/xappAmN-wb8
New structural and functional insights from in-cell NMR.
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