[NMR paper] A multi-omics approach based on 1H-NMR metabonomics combined with target protein analysis to reveal the mechanism of RIAISs on cervical carcinoma patients
A multi-omics approach based on 1H-NMR metabonomics combined with target protein analysis to reveal the mechanism of RIAISs on cervical carcinoma patients
Cervical carcinoma (CC) is the fourth most common cancer in females and radiotherapy is always as the definitive therapy for cervical cancer patients who are not suitable for surgery. Radiation-induced acute intestinal symptoms (RIAISs) occur in 50-80% of cervical cancer patients. Some research shows that RIAISs may relate to inflammatory reaction by radiotherapy but the action mechanism is also not clearly and the details of the molecular mechanism are still urgently needed. In this paper,...
[NMR paper] [Anti-inflammatory mechanism of Crepis crocea based on NF-?B signaling pathway and ~1H-NMR metabonomics].
.
Related Articles .
Zhongguo Zhong Yao Za Zhi. 2020 Feb;45(4):946-954
Authors: Miao YL, He P, Zhang WX, Zhang WZ, Feng M, Ni Y
Abstract
Based on ~1H-NMR metabonomics technique and Western blot assay, the anti-inflammatory mechanism of Crepis crocea was discussed. In this study, male SD rats were treated with water extract(2.5 g·kg~(-1)) and dexamethasone acetate(6.25×10~(-4) g·kg~(-1)) for one week, and the inflammation model was induced by lipopolysaccharide(LPS). Then the counts of inflammatory cells white blood ceel(WBC),...
nmrlearner
Journal club
0
04-03-2020 09:41 PM
[NMR paper] 1H-NMR-based metabolomics approach reveals metabolic mechanism of (-)-5-hydroxy-equol against hepatocellular carcinoma cells in vitro.
1H-NMR-based metabolomics approach reveals metabolic mechanism of (-)-5-hydroxy-equol against hepatocellular carcinoma cells in vitro.
1H-NMR-based metabolomics approach reveals metabolic mechanism of (-)-5-hydroxy-equol against hepatocellular carcinoma cells in vitro.
J Proteome Res. 2018 Mar 28;:
Authors: Gao L, Wang KX, Zhang NN, Li JQ, Qin XM, Wang XL
Abstract
1H-NMR-based metabolomics can rapidly detect metabolic shift under various stimulus, thus it facilitated the dissection of the therapeutic mechanisms of compounds....
nmrlearner
Journal club
0
03-29-2018 07:42 PM
[NMR paper] Renal Cell Carcinoma: A Study through NMR-Based Metabolomics Combined with Transcriptomics.
Renal Cell Carcinoma: A Study through NMR-Based Metabolomics Combined with Transcriptomics.
Related Articles Renal Cell Carcinoma: A Study through NMR-Based Metabolomics Combined with Transcriptomics.
Diseases. 2016 Jan 22;4(1):
Authors: Ragone R, Sallustio F, Piccinonna S, Rutigliano M, Vanessa G, Palazzo S, Lucarelli G, Ditonno P, Battaglia M, Fanizzi FP, Schena FP
Abstract
Renal cell carcinoma (RCC) is a heterogeneous cancer often showing late symptoms. Until now, some candidate protein markers have been proposed for its...
nmrlearner
Journal club
0
09-24-2017 06:16 AM
[NMR paper] A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
Related Articles A novel approach based on low-field NMR for the detection of the pathological components of sputum in cystic fibrosis patients.
Magn Reson Med. 2017 Aug 22;:
Authors: Abrami M, Ascenzioni F, Di Domenico EG, Maschio M, Ventura A, Confalonieri M, Di Gioia S, Conese M, Dapas B, Grassi G, Grassi M
Abstract
PURPOSE: Development of a reliable, simple method to monitor lung condition in...
nmrlearner
Journal club
0
08-25-2017 04:11 AM
[NMR paper] An Omics Approach to Rational Feed: Enhancing Growth in CHO Cultures with NMR Metabolomics and 2D-DIGE Proteomics.
An Omics Approach to Rational Feed: Enhancing Growth in CHO Cultures with NMR Metabolomics and 2D-DIGE Proteomics.
Related Articles An Omics Approach to Rational Feed: Enhancing Growth in CHO Cultures with NMR Metabolomics and 2D-DIGE Proteomics.
J Biotechnol. 2016 Aug 2;
Authors: Blondeel EJ, Ho R, Schulze S, Sokolenko S, Guillemette SR, Slivac I, Durocher Y, Guillemette JG, McConkey BJ, Chang D, Aucoin MG
Abstract
Expression of recombinant proteins exerts stress on cell culture systems, affecting the expression of...
nmrlearner
Journal club
0
08-09-2016 02:42 PM
[NMR paper] Metabolomics analysis of cervical cancer, cervical intraepithelial neoplasia and chronic cervicitis by 1H NMR spectroscopy.
Metabolomics analysis of cervical cancer, cervical intraepithelial neoplasia and chronic cervicitis by 1H NMR spectroscopy.
Related Articles Metabolomics analysis of cervical cancer, cervical intraepithelial neoplasia and chronic cervicitis by 1H NMR spectroscopy.
Eur J Gynaecol Oncol. 2015;36(2):174-80
Authors: Ye N, Liu C, Shi P
Abstract
Metabolomics profiles of serum samples from women with chronic cervicitis, cervical intraepithelial neoplasia (CIN), and cervical cancer were characterized by proton nuclear magnetic resonance...
nmrlearner
Journal club
0
08-19-2015 03:24 PM
[NMR paper] (1)H NMR-based metabolomics studies of urine reveal differences between type 1 diabetic patients with high and low HbAc1 values.
(1)H NMR-based metabolomics studies of urine reveal differences between type 1 diabetic patients with high and low HbAc1 values.
(1)H NMR-based metabolomics studies of urine reveal differences between type 1 diabetic patients with high and low HbAc1 values.
J Pharm Biomed Anal. 2013 Apr 22;83C:43-48
Authors: Deja S, Barg E, M?ynarz P, Basiak A, Willak-Janc E
Abstract
The aim of this study was to investigate relation between level of HbAc1 and concentration of metabolites in urine of T1D patients. To test this hypothesis the (1)H NMR...
nmrlearner
Journal club
0
05-25-2013 12:05 PM
[NMR paper] Using a Fragment-Based Approach To Target Protein-Protein Interactions.
Using a Fragment-Based Approach To Target Protein-Protein Interactions.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary-Button_120x27px_FullText.gif http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2251-04-WileyOnlineLibrary-Button_120x27px_FullTextFree.gif Related Articles Using a Fragment-Based Approach To Target Protein-Protein Interactions.
Chembiochem. 2013 Jan 23;
Authors: Scott DE, Ehebauer MT, Pukala T, Marsh M, Blundell TL, Venkitaraman AR, Abell C, Hyvönen M
...