[NMR paper] Metabolome of different cultivars of peas, lentils, faba beans and lupins - An (1)H NMR spectroscopic exploration of their sensory attributes and potential biofunctionality
Metabolome of different cultivars of peas, lentils, faba beans and lupins - An (1)H NMR spectroscopic exploration of their sensory attributes and potential biofunctionality
The transition to a more plant-based diet embraces a higher consumption of diversified pulses. Understanding the chemical composition of pulses is crucial to decipher their biofunctionality. This study analyzed 14 different cultivars of 4 types of pulses (pea, lentil, faba bean, and lupin) using NMR-based metabolomics. Sucrose, glutamate, and citrate were the metabolites representing the most abundant polar chemical classes (carbohydrates, amino acids, and organic acids). Lupin had a higher...
[NMR paper] Integrated transcriptome and (1)H NMR-based metabolome to explore the potential mechanism of Spodoptera litura in response to flupyrimin
Integrated transcriptome and (1)H NMR-based metabolome to explore the potential mechanism of Spodoptera litura in response to flupyrimin
Flupyrimin (FLP) is a novel class of insecticide acting on insect nicotinic acetylcholine receptor (nAChR) and shows robust insecticidal activity. However, the toxicological effects of FLP on Spodoptera litura have not been revealed. In this study, the results showed that the larval survival rate decreased significantly with increasing concentration of FLP. The hematoxylin-eosin (HE) staining showed that FLP exposure damages the structure of the larval...
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10-31-2024 04:30 AM
Enabling site-specific NMR investigations of therapeutic FabÂ*using a cell-free based isotopic labeling approach:Â*application to anti-LAMP1 Fab
Enabling site-specific NMR investigations of therapeutic FabÂ*using a cell-free based isotopic labeling approach:Â*application to anti-LAMP1 Fab
Abstract
Monoclonal antibodies (mAbs) are biotherapeutics that have achieved outstanding success in treating many life-threatening and chronic diseases. The recognition of an antigen is mediated by the fragment antigen binding (Fab) regions composed by four different disulfide bridge-linked immunoglobulin domains. NMR is a powerful method to assess the integrity, the structure and interaction of Fabs, but...
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03-28-2024 07:10 PM
[NMR paper] Unraveling Compositional Study, Chemometric Analysis, and Cell-Based Antioxidant Potential of Selective High Nutraceutical Value Amaranth Cultivars Using a GC-MS and NMR-Based Metabolomics Approach
Unraveling Compositional Study, Chemometric Analysis, and Cell-Based Antioxidant Potential of Selective High Nutraceutical Value Amaranth Cultivars Using a GC-MS and NMR-Based Metabolomics Approach
Amaranthus (family Amaranthaceae) is a potentially nutritious pseudocereal also known as a functional food owing to its high nutritional quality grains especially rich in essential amino acids. Emerging study, however, unambiguously indicates that apart from essential nutrients like protein, other phytochemicals present in amaranth seeds provide excellent health benefits. Squalene is one such...
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12-27-2023 08:40 AM
[NMR paper] Bean cultivars (Phaseolus vulgaris L.) under the spotlight of NMR metabolomics
Bean cultivars (Phaseolus vulgaris L.) under the spotlight of NMR metabolomics
The seeds of Phaseolus vulgaris are a rich source of protein consumed around the world and are considered as the most important source of proteins and antioxidants in the Mexican diet. This work reports on the 1H NMR metabolomics profiling of the cultivars Peruano (FPe), Pinto (FPi), Flor de mayo (FM), Negro (FN) and Flor de junio (FJ). Total phenolics, total flavonoids and total protein contents were determined to complement the nutritional facts in seeds and leaves. According to our results,...
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Full of beans: NMR spectroscopy confirms coffee
Full of beans: NMR spectroscopy confirms coffee
http://www.spectroscopynow.com/common/images/thumbnails/14ae43d65ef.jpgAn international team from Colombia and Germany has demonstrated how to use NMR spectroscopy to identify adulteration or contamination of coffee beans based on country of origin, a useful tool in the fight against food fraud in a high-value market.
Read the rest at Spectroscopynow.com
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01-15-2015 04:31 AM
[NMR paper] (1)H NMR spectroscopic studies on the characterization of renal cell lines and identification of novel potential markers of in vitro nephrotoxicity.
(1)H NMR spectroscopic studies on the characterization of renal cell lines and identification of novel potential markers of in vitro nephrotoxicity.
Related Articles (1)H NMR spectroscopic studies on the characterization of renal cell lines and identification of novel potential markers of in vitro nephrotoxicity.
Biomarkers. 1996;1(1):35-43
Authors: Anthony ML, McDowell PC, Gray TJ, Blackmore M, Nicholson JK
Abstract
Abstract Cell cultures are increasingly used in the evaluation of chemically-induced nephrotoxicity. The utili of renal cell...
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07-31-2013 12:00 PM
Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses
Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses
Abstract 1H NMR (nuclear magnetic resonance spectroscopy) has been used for metabolomic analysis of â??Rieslingâ?? and â??Mueller-Thurgauâ?? white wines from the German Palatinate region. Diverse two-dimensional NMR techniques have been applied for the identification of metabolites, including phenolics. It is shown that sensory analysis correlates with NMR-based metabolic profiles of wine. 1H NMR data in combination...