[NMR paper] Metabolite Profiling by UPLC-MSE, NMR, and Antioxidant Properties of Amazonian Fruits: Mamey Apple (Mammea Americana), Camapu (Physalis Angulata), and Uxi (Endopleura Uchi).
Metabolite Profiling by UPLC-MSE, NMR, and Antioxidant Properties of Amazonian Fruits: Mamey Apple (Mammea Americana), Camapu (Physalis Angulata), and Uxi (Endopleura Uchi).
Related ArticlesMetabolite Profiling by UPLC-MSE, NMR, and Antioxidant Properties of Amazonian Fruits: Mamey Apple (Mammea Americana), Camapu (Physalis Angulata), and Uxi (Endopleura Uchi).
Molecules. 2020 Jan 15;25(2):
Authors: Lima LGB, Montenegro J, Abreu JP, Santos MCB, Nascimento TPD, Santos MDS, Ferreira AG, Cameron LC, Ferreira MSL, Teodoro AJ
Abstract
The metabolite profiling associated with the antioxidant potential of Amazonian fruits represents an important step to the bioactive compound's characterization due to the large biodiversity in this region. The comprehensive bioactive compounds profile and antioxidant capacities of mamey apple (Mammea americana), camapu (Physalis angulata), and uxi (Endopleura uchi) was determined for the first time. Bioactive compounds were characterized by ultra-performance liquid chromatography coupled to high resolution mass spectrometry (UPLC-MSE) in aqueous and ethanolic extracts. Globally, a total of 293 metabolites were tentatively identified in mamey apple, campau, and uxi extracts. The main classes of compounds in the three species were terpenoids (61), phenolic acids (58), and flavonoids (53). Ethanolic extracts of fruits showed higher antioxidant activity and total ion abundance of bioactive compounds than aqueous. Uxi had the highest values of phenolic content (701.84 mg GAE/100 g), ABTS (1602.7 ?mol Trolox g-1), and ORAC (15.04 ?mol Trolox g-1). Mamey apple had the highest results for DPPH (1168.42 ?mol TE g-1) and FRAP (1381.13 ?mol FSE g-1). Nuclear magnetic resonance (NMR) spectroscopy results showed that sugars and lipids were the substances with the highest amounts in mamey apple and camapu. Data referring to chemical characteristics and antioxidant capacity of these fruits can contribute to their economic exploitation.
[NMR paper] Systematic identification of protein-metabolite interactions in complex metabolite mixtures by ligand-detected NMR spectroscopy.
Systematic identification of protein-metabolite interactions in complex metabolite mixtures by ligand-detected NMR spectroscopy.
Systematic identification of protein-metabolite interactions in complex metabolite mixtures by ligand-detected NMR spectroscopy.
Biochemistry. 2016 Apr 11;
Authors: Nikolaev YV, Kochanowski K, Link H, Sauer U, Allain FH
Abstract
Protein-metabolite interactions play a vital role in the regulation of numerous cellular processes. Consequently, identifying such interactions is a key prerequisite for...
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04-12-2016 09:12 PM
[NMR paper] NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
NMR-based metabolite profiling of human milk: a pilot study of methods for investigating compositional changes during lactation.
Biochem Biophys Res Commun. 2015 Dec 1;
Authors: Wu J, Domellöf M, Zivkovic AM, Larsson G, Öhman A, Nording ML
Abstract
Low-molecular-weight metabolites in human milk are gaining increasing interest in studies of infant nutrition. In the present study, the milk metabolome...
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12-15-2015 08:09 PM
Journal Highlight: 1H and 13C NMR-based sugar profiling with chemometric analysis and antioxidant activity of herbhoneys and honeys
Journal Highlight: 1H and 13C NMR-based sugar profiling with chemometric analysis and antioxidant activity of herbhoneys and honeys
http://www.spectroscopynow.com/common/images/thumbnails/1447e6dff3b.jpg1H and 13C NMR spectroscopy coupled with chemometric analysis (PCA and PLS-DA) and antioxidant assays were used to study 25 samples of Polish herbhoneys and honeys.
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03-03-2014 04:55 PM
[NMR paper] (1)H NMR-Based Metabolite Profiling of Plasma in a Rat Model of Chronic Kidney Disease.
(1)H NMR-Based Metabolite Profiling of Plasma in a Rat Model of Chronic Kidney Disease.
(1)H NMR-Based Metabolite Profiling of Plasma in a Rat Model of Chronic Kidney Disease.
PLoS One. 2014 Jan 20;9(1):e85445
Authors: Kim JA, Choi HJ, Kwon YK, Ryu do H, Kwon TH, Hwang GS
Abstract
Chronic kidney disease (CKD) is characterized by the gradual loss of the kidney function to excrete wastes and fluids from the blood. (1)H NMR-based metabolomics was exploited to investigate the altered metabolic pattern in rats with CKD induced by surgical...
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01-28-2014 11:53 AM
[NMR paper] 1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
Biomed Res Int. 2013;2013:329058
Authors: Jana SK, Dutta M, Joshi M, Srivastava S, Chakravarty B, Chaudhury K
Abstract
Accumulating evidence indicates the active role of oxidative stress in the development of endometriosis; however, the mechanism of reactive oxygen species...
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08-29-2013 01:53 PM
[NMR paper] Comparison of GC-MS and NMR for metabolite profiling of rice subjected to submergence stress.
Comparison of GC-MS and NMR for metabolite profiling of rice subjected to submergence stress.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Comparison of GC-MS and NMR for metabolite profiling of rice subjected to submergence stress.
J Proteome Res. 2013 Feb 1;12(2):898-909
Authors: Barding GA, Béni S, Fukao T, Bailey-Serres J, Larive CK
Abstract
Natural disasters such as drought, extreme temperatures, and flooding can severely impact crop production....
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07-06-2013 09:57 PM
Nuclear magnetic resonance (NMR)-based drug metabolite profiling.
Nuclear magnetic resonance (NMR)-based drug metabolite profiling.
Nuclear magnetic resonance (NMR)-based drug metabolite profiling.
Methods Mol Biol. 2011;708:299-319
Authors: Lenz EM
The identification of drug metabolites in biofluids such as urine, plasma and bile is an important step in drug discovery and development. Proton nuclear magnetic resonance ((1)H-NMR) spectroscopy can provide detailed information regarding the structural transformation of a compound as a consequence of metabolism. However, successful identification of drug...
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04-09-2011 10:57 AM
[NMR paper] In vivo 13C NMR metabolite profiling: potential for understanding and assessing conifer seed quality.
In vivo 13C NMR metabolite profiling: potential for understanding and assessing conifer seed quality.
Related Articles In vivo 13C NMR metabolite profiling: potential for understanding and assessing conifer seed quality.
J Exp Bot. 2005 Aug;56(418):2253-65
Authors: Terskikh VV, Feurtado JA, Borchardt S, Giblin M, Abrams SR, Kermode AR
High-resolution 13C MAS NMR spectroscopy was used to profile a range of primary and secondary metabolites in vivo in intact whole seeds of eight different conifer species native to North America, including six of...
Metabolite Profiling by UPLC-MSE, NMR, and Antioxidant Properties of Amazonian Fruits: Mamey Apple (Mammea Americana), Camapu (Physalis Angulata), and Uxi (Endopleura Uchi).
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