NMR paper Metabolite Analyses Using Nuclear Magnetic Resonance (NMR) Spectroscopy in Plasma of Patients with Prostate Cancer

		BioNMR > Educational resources > Journal club
[NMR paper] Metabolite Analyses Using Nuclear Magnetic Resonance (NMR) Spectroscopy in Plasma of Patients with Prostate Cancer

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

06-01-2023, 05:37 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,777

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Metabolite Analyses Using Nuclear Magnetic Resonance (NMR) Spectroscopy in Plasma of Patients with Prostate Cancer

Metabolite Analyses Using Nuclear Magnetic Resonance (NMR) Spectroscopy in Plasma of Patients with Prostate Cancer

Nuclear magnetic resonance (NMR) spectroscopy enables the detection and the quantification of a large range of molecules, including low-molecular-weight metabolites and lipids. NMR spectroscopy is a powerful approach when applied to the high-throughput analysis of plasma or serum samples allowing, in addition, the detection of total proteins, lipoproteins, and signals arising from the glycosylation of circulating acute-phase proteins. Here, we describe the usage of NMR spectroscopy for profiling...

More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
[NMR paper] NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics. NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics. Related Articles NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics. Prostate. 2016 Sep;76(12):1106-19 Authors: Kumar D, Gupta A, Mandhani A, Sankhwar SN Abstract BACKGROUND: To address the shortcomings of digital rectal examinations (DRE), serum prostate-specific antigen (PSA), and trans-rectal ultrasound (TRUS) for precise determination of prostate cancer (PC) and differentiation from benign prostatic...	nmrlearner	Journal club	0	07-14-2017 01:53 PM
Journal Highlight: NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics Journal Highlight: NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics http://www.spectroscopynow.com/common/images/thumbnails/1563b836aed.jpgThe application of 1H NMR spectroscopy of 52 serum metabolites as a surrogate tactic for probing and predicting prostate cancer and benign prostatic hyperplasia is on a par with LC/MS and histopathological examination. Read the rest at Spectroscopynow.com	nmrlearner	General	0	08-01-2016 10:03 AM
Systematic Identification of Protein–Metabolite Interactions in Complex MetaboliteMixtures by Ligand-Detected Nuclear Magnetic Resonance Spectroscopy Systematic Identification of Protein–Metabolite Interactions in Complex MetaboliteMixtures by Ligand-Detected Nuclear Magnetic Resonance Spectroscopy http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.5b01291/20160425/images/medium/bi-2015-012916_0005.gif Biochemistry DOI: 10.1021/acs.biochem.5b01291 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/TQ5IVPOPNRw More...	nmrlearner	Journal club	0	04-26-2016 12:14 PM
Metabolic imaging of patients with prostate cancer using hyperpolarized [1-(1)(3)C]pyruvate From The DNP-NMR Blog: Metabolic imaging of patients with prostate cancer using hyperpolarized pyruvate Nelson, S.J., et al., Metabolic imaging of patients with prostate cancer using hyperpolarized pyruvate. Sci Transl Med, 2013. 5(198): p. 198ra108. http://www.ncbi.nlm.nih.gov/pubmed/23946197	nmrlearner	News from NMR blogs	0	12-29-2015 02:29 AM
[NMR paper] Magnetic susceptibility to measure total protein concentration from NMR metabolite spectra: Demonstration on blood plasma. Magnetic susceptibility to measure total protein concentration from NMR metabolite spectra: Demonstration on blood plasma. http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary-Button_120x27px_FullText.gif Related Articles Magnetic susceptibility to measure total protein concentration from NMR metabolite spectra: Demonstration on blood plasma. Magn Reson Med. 2014 Mar 17; Authors: Jupin M, Michiels PJ, Girard FC, Wijmenga SS Abstract PURPOSE: Accurate metabolite and...	nmrlearner	Journal club	0	03-19-2014 10:43 PM
[NMR tweet] Imaging of Prostate and Breast Cancer Bone Metastases Using Magnetic Resonance Imaging and Nuclear Medicine T... http://1.usa.gov/fZBOle Imaging of Prostate and Breast Cancer Bone Metastases Using Magnetic Resonance Imaging and Nuclear Medicine T... http://1.usa.gov/fZBOle Published by BreastCaStudy (Breast Cancer Study) on 2011-04-21T13:43:49Z Source: Twitter	nmrlearner	Twitter NMR	0	04-21-2011 01:50 PM
Nuclear magnetic resonance (NMR)-based drug metabolite profiling. Nuclear magnetic resonance (NMR)-based drug metabolite profiling. Nuclear magnetic resonance (NMR)-based drug metabolite profiling. Methods Mol Biol. 2011;708:299-319 Authors: Lenz EM The identification of drug metabolites in biofluids such as urine, plasma and bile is an important step in drug discovery and development. Proton nuclear magnetic resonance ((1)H-NMR) spectroscopy can provide detailed information regarding the structural transformation of a compound as a consequence of metabolism. However, successful identification of drug...	nmrlearner	Journal club	0	04-09-2011 10:57 AM
[NMR tweet] For Women With Breast Cancer, It's Buyer Beware: NMR (nuclear magnetic resonance) scan of woman showing cancer i... http://bit.ly/fS5trE For Women With Breast Cancer, It's Buyer Beware: NMR (nuclear magnetic resonance) scan of woman showing cancer i... http://bit.ly/fS5trE Published by Cancer4breast (Sue Stock-Cojocaru) on 2011-01-04T02:22:58Z Source: Twitter	nmrlearner	Twitter NMR	0	01-04-2011 02:29 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off