Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids

		BioNMR > Educational resources > Journal club
Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

03-09-2012, 09:16 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids

Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids

Publication year: 2012
Source:Progress in Nuclear Magnetic Resonance Spectroscopy, Volume 62

Iola F. Duarte, Ana M. Gil

More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids Publication year: 2011 Source: Progress in Nuclear Magnetic Resonance Spectroscopy, Available online 29 November 2011</br> Iola F.Duarte, Ana M.Gil</br> More...	nmrlearner	Journal club	0	12-01-2011 12:33 PM
Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. J Proteome Res. 2010 Dec 3;9(12):6729-39 Authors: Szeto SS, Reinke SN, Sykes BD, Lemire BD Metabolomics is a powerful method of examining the intricate connections between mutations, metabolism, and disease. Metabolic...	nmrlearner	Journal club	0	05-25-2011 07:01 PM
1H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system 1H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system Abstract Hypoxia can promote invasive behavior in cancer cells and alters the response to therapeutic intervention as a result of changes in the expression many genes, including genes involved in intermediary metabolism. Although metabolomics technologies are capable of simultaneously measuring a wide range of metabolites in an untargeted manner, these methods have been relatively under utilized in the study of cancer cell responses to hypoxia. Thus, 1H NMR metabolomics was...	nmrlearner	Journal club	0	03-09-2011 04:19 AM
(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system. (1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system. (1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system. J Biomol NMR. 2011 Mar 4; Authors: Weljie AM, Bondareva A, Zang P, Jirik FR Hypoxia can promote invasive behavior in cancer cells and alters the response to therapeutic intervention as a result of changes in the expression many genes, including genes involved in intermediary metabolism. Although metabolomics...	nmrlearner	Journal club	0	03-05-2011 01:02 PM
Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine. Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine. Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine. J Neuroimmune Pharmacol. 2010 Dec;5(4):574-81 Authors: El Ghazi I, Sheng WS, Hu S, Reilly BG, Lokensgard JR, Rock RB, Peterson PK, Wilcox GL, Armitage IM Microglial cells play a major role in host defense of the central nervous system. Once activated, several functional properties are up-regulated including migration, phagocytosis, and...	nmrlearner	Journal club	0	03-01-2011 12:14 PM
[NMR tweet] For Women With Breast Cancer, It's Buyer Beware: NMR (nuclear magnetic resonance) scan of woman showing cancer i... http://bit.ly/fS5trE For Women With Breast Cancer, It's Buyer Beware: NMR (nuclear magnetic resonance) scan of woman showing cancer i... http://bit.ly/fS5trE Published by Cancer4breast (Sue Stock-Cojocaru) on 2011-01-04T02:22:58Z Source: Twitter	nmrlearner	Twitter NMR	0	01-04-2011 02:29 AM
[NMR paper] Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR a Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method. Related Articles Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method. Anticancer Res. 1996 May-Jun;16(3B):1375-80 Authors: Katz-Brull R, Degani H The mechanism and kinetics of choline transport and phosphorylation in MCF7 human breast cancer cells was studied by 31P, 13C and 2H NMR, applying the zero trans method. Choline was transported by a...	nmrlearner	Journal club	0	08-22-2010 02:27 PM
spectroscopy to fingerprint a person's metabolic phenotype spectroscopy to fingerprint a person's metabolic phenotype Now, NMR spectroscopy has revealed that an "omic" other than genomic could provide a unique view of each of the 6.7 billion people on earth - their metabonomic fingerprint. More...	nmrlearner	Online News	0	08-19-2010 01:47 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off