Patient-derived cancer cells cultured in vitro is a cornerstone for cancer metabolism research. More recently, the introduction of organoids has provided the research community with a more versatile model system. Physiological structure and organization of the cell source tissue is maintained in organoids, representing a closer link to in vivo tumor models. High resolution magic angle spinning MR spectroscopy (HR MAS MRS) is a commonly applied analytical approach for metabolic profiling of...
[NMR paper] Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Related Articles Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Clin Chim Acta. 2020 Jul 21;:
Authors: Ge S, Zhang Q, Tian Y, Hao L, Duan J, Zhang B
Abstract
BACKGROUND: Protein arginine methyltransferase 5 (PRMT5) belongs to a large family of protein arginine methyltransferases (PRMTs) that play essential role in gene transcription and regulate tumorigenesis. However, the role of PRMT5 in the regulation of cancer cell metabolism remains unclear.
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07-27-2020 09:21 PM
[NMR paper] Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
J Proteome Res. 2019 07 05;18(7):2826-2834
Authors: Dutta P, Perez MR, Lee J, Kang Y, Pratt M, Salzillo TC, Weygand J, Zacharias NM, Gammon ST, Koay EJ, Kim M,...
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07-22-2020 05:30 AM
[NMR paper] Anti-cancer effects of emodin on HepG2 cells as revealed by 1H-NMR based metabolic profiling.
Anti-cancer effects of emodin on HepG2 cells as revealed by 1H-NMR based metabolic profiling.
Related Articles Anti-cancer effects of emodin on HepG2 cells as revealed by 1H-NMR based metabolic profiling.
J Proteome Res. 2018 Apr 20;:
Authors: Xing YX, Li MH, Tao L, Ruan LY, Hong W, Chen C, Zhao WL, Xu H, Chen JF, Wang JS
Abstract
Hepatic carcinoma is one of the most common cancers in the world with a high incidence. Emodin is an anthraquinone derived from Polygonum multiflorum Thunb, possessing anti-cancer activity. The purpose...
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04-21-2018 10:14 AM
[NMR paper] NMR-Based Identification of Metabolites in Polar and Non-Polar Extracts of Avian Liver.
NMR-Based Identification of Metabolites in Polar and Non-Polar Extracts of Avian Liver.
NMR-Based Identification of Metabolites in Polar and Non-Polar Extracts of Avian Liver.
Metabolites. 2017 Nov 16;7(4):
Authors: Fathi F, Brun A, Rott KH, Falco Cobra P, Tonelli M, Eghbalnia HR, Caviedes-Vidal E, Karasov WH, Markley JL
Abstract
Metabolites present in liver provide important clues regarding the physiological state of an organism. The aim of this work was to evaluate a protocol for high-throughput NMR-based analysis of polar and...
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11-17-2017 12:42 PM
[NMR paper] Impact of chemotherapy on metabolic reprogramming: Characterization of the metabolic profile of breast cancer MDA-MB-231 cells using (1)H HR-MAS NMR spectroscopy.
Impact of chemotherapy on metabolic reprogramming: Characterization of the metabolic profile of breast cancer MDA-MB-231 cells using (1)H HR-MAS NMR spectroscopy.
Related Articles Impact of chemotherapy on metabolic reprogramming: Characterization of the metabolic profile of breast cancer MDA-MB-231 cells using (1)H HR-MAS NMR spectroscopy.
J Pharm Biomed Anal. 2017 Sep 12;146:324-328
Authors: Maria RM, Altei WF, Selistre-de-Araujo HS, Colnago LA
Abstract
Doxorubicin, cisplatin, and tamoxifen are part of many chemotherapeutic...
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09-16-2017 09:58 PM
[NMR paper] Quantitative Metabolomic Profiling of Plasma, Urine and Liver Extracts by 1H NMR Spectroscopy Characterizes Different Stages of Atherosclerosis in Hamsters.
Quantitative Metabolomic Profiling of Plasma, Urine and Liver Extracts by 1H NMR Spectroscopy Characterizes Different Stages of Atherosclerosis in Hamsters.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Quantitative Metabolomic Profiling of Plasma, Urine and Liver Extracts by 1H NMR Spectroscopy Characterizes Different Stages of Atherosclerosis in Hamsters.
J Proteome Res. 2016 Aug 29;
Authors: Guo W, Jiang C, Yang L, Li T, Liu X, Jin M, Qu K, Chen H, Jin X, Liu H, Zhu...
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08-31-2016 02:34 PM
[NMR paper] (1)H- and (13)C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.
(1)H- and (13)C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.
Related Articles (1)H- and (13)C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.
J Neural Transm. 2015 Mar 6;
Authors: Doert A, Pilatus U, Zanella F, Müller WE, Eckert GP
Abstract
Biochemical alterations underlying the symptoms and pathomechanisms of Alzheimer's disease (AD) are not fully understood. However, alterations of glucose metabolism and...
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03-08-2015 01:07 AM
Colon cancer calculated: Metabolic profiling
Colon cancer calculated: Metabolic profiling
http://www.spectroscopynow.com/common/images/thumbnails/14077d20717.jpgNuclear magnetic resonance (NMR) spectroscopy can be used to obtain a metabolic fingerprint of cancer of the bowel and so determine how far advanced the disease is, according to UK researchers.
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Metabolic profiling of colorectal cancer organoids: a comparison between HR MAS MRS and solution NMR spectroscopy of polar extracts
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