Enhanced-sensitivity NMR could reveal new clues to how proteins fold - Phys.Org
Enhanced-sensitivity NMR could reveal new clues to how proteins fold - Phys.Org
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Phys.Org
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Enhanced-sensitivity NMR could reveal new clues to how proteins fold
Phys.Org
Until now, it has been difficult to fully characterize the different structures that proteins can take on in their natural environments. However, using a new technique known as sensitivity-enhanced nuclear magnetic resonance (NMR), MIT researchers have ...
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10-09-2015 04:49 PM
Characterization of Mapcho Bicelles - Model Membranes for the NMR Study of Membrane Proteins and Peptides
Characterization of Mapcho Bicelles - Model Membranes for the NMR Study of Membrane Proteins and Peptides
Publication date: 28 January 2014
Source:Biophysical Journal, Volume 106, Issue 2, Supplement 1</br>
Author(s): Maïwenn Beaugrand , Alexandre A. Arnold , Philip T.F. Williamson , Isabelle Marcotte</br>
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01-29-2014 12:50 AM
A trick to fold proteins more quickly: 'Clever' technique speeds up the ... - Science Daily (press release)
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A trick to fold proteins more quickly: 'Clever' technique speeds up the ...
Science Daily (press release)
"We exploit the experimental data obtained observing the proteins through nuclear magnetic resonance, and use them to create restraints to be applied to the model," explained Laio, who has coordinated the research published in Proceedings of the ...
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A trick to fold proteins more quickly: 'Clever' technique speeds up the ... - Science Daily (press release)
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nmrlearner
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05-08-2013 02:49 PM
A trick to fold proteins more quickly - PhysOrg.com - Phys.Org
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A trick to fold proteins more quickly - PhysOrg.com
Phys.Org
"We exploit the experimental data obtained observing the proteins through nuclear magnetic resonance, and use them to create restraints to be applied to the model", explained Laio, who has coordinated the research published in Proceedings of the ...
A trick to fold proteins more quickly - PhysOrg.com - Phys.Org
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nmrlearner
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05-08-2013 02:49 PM
Fold it: Solid-state NMR unravels proteins - spectroscopyNOW.com
Fold it: Solid-state NMR unravels proteins - spectroscopyNOW.com
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Fold it: Solid-state NMR unravels proteins
spectroscopyNOW.com
Researchers have developed a novel solid-state NMR spectroscopic method that uses paramagnetic tags to help them visualize the shape of protein molecules. The technique could be used to help scientists understand the properties of various biological ...
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nmrlearner
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04-01-2012 03:58 PM
Fold it: Solid-state NMR unravels proteins
Fold it: Solid-state NMR unravels proteins
Researchers have developed a novel solid-state NMR spectroscopic method that uses paramagnetic tags to help them visualize the shape of protein molecules. The technique could be used to help scientists understand the properties of various biological molecules under normal, healthy conditions and also in those that are involved in a range of diseases.
Source: Spectroscopynow.com
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04-01-2012 03:58 PM
Rapid measurement of residual dipolar couplings for fast fold elucidation of proteins
Rapid measurement of residual dipolar couplings for fast fold elucidation of proteins
Abstract It has been demonstrated that protein folds can be determined using appropriate computational protocols with NMR chemical shifts as the sole source of experimental restraints. While such approaches are very promising they still suffer from low convergence resulting in long computation times to achieve accurate results. Here we present a suite of time- and sensitivity optimized NMR experiments for rapid measurement of up to six RDCs per residue. Including such an RDC data set, measured in less...
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09-17-2011 10:20 AM
[NMR paper] An approach to global fold determination using limited NMR data from larger proteins
An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types.
An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types.
J Biomol NMR. 1996 Oct;8(3):360-8
Authors: Smith BO, Ito Y, Raine A, Teichmann S, Ben-Tovim L, Nietlispach D, Broadhurst RW, Terada T, Kelly M, Oschkinat H, Shibata T, Yokoyama S, Laue ED
A combination of calculation and experiment is used to demonstrate that the global fold of...