Mohammad T. Mazhab-Jafari, Christopher B. Marshall, Peter B. Stathopulos, Yoshihiro Kobashigawa, Vuk Stambolic, Lewis E. Kay, Fuyuhiko Inagaki and Mitsuhiko Ikura
Journal of the American Chemical Society
DOI: 10.1021/ja312508w
[NMR paper] Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc.
Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc.
Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc.
J Am Chem Soc. 2013 Feb 14;
Authors: Mazhab-Jafari MT, Marshall CB, Stathopulos PB, Kobashigawa Y, Stambolic V, Kay LE, Inagaki F, Ikura M
Abstract
Like most Ras superfamily proteins, the GTPase domain of Ras homolog enriched in brain (Rheb) is tethered to cellular membranes through a...
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02-16-2013 08:00 PM
[NMR paper] Detergent/Nanodisc screening for high-resolution NMR studies of an integral membrane protein containing a cytoplasmic domain.
Detergent/Nanodisc screening for high-resolution NMR studies of an integral membrane protein containing a cytoplasmic domain.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles Detergent/Nanodisc screening for high-resolution NMR studies of an integral membrane protein containing a cytoplasmic domain.
PLoS One. 2013;8(1):e54378
Authors: Tzitzilonis C, Eichmann C, Maslennikov I, Choe...
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02-03-2013 10:19 AM
When detergent meets bilayer: birth and coming of age of lipid bicelles
When detergent meets bilayer: birth and coming of age of lipid bicelles
Available online 23 January 2013
Publication year: 2013
Source:Progress in Nuclear Magnetic Resonance Spectroscopy</br>
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Graphical abstract
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01-24-2013 09:57 AM
An evaluation tool for FKBP12-dependent and -independent mTOR inhibitors using a combination of FKBP-mTOR fusion protein, DSC and NMR.
An evaluation tool for FKBP12-dependent and -independent mTOR inhibitors using a combination of FKBP-mTOR fusion protein, DSC and NMR.
An evaluation tool for FKBP12-dependent and -independent mTOR inhibitors using a combination of FKBP-mTOR fusion protein, DSC and NMR.
Protein Eng Des Sel. 2011 Sep 6;
Authors: Sekiguchi M, Kobashigawa Y, Kawasaki M, Yokochi M, Kiso T, Suzumura KI, Mori K, Teramura T, Inagaki F
Abstract
Mammalian target of rapamycin (mTOR), a large multidomain protein kinase, regulates cell growth and metabolism in...
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09-09-2011 06:42 PM
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
Structure. 2010 Oct 13;18(10):1280-8
Authors: Kalli AC, Wegener KL, Goult BT, Anthis NJ, Campbell ID, Sansom MS
Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin ? cytoplasmic tail. Here, we use coarse-grained molecular dynamic...
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03-03-2011 12:34 PM
[NMR paper] Dynamic pictures of membrane proteins in two-dimensional crystal, lipid bilayer and d
Dynamic pictures of membrane proteins in two-dimensional crystal, lipid bilayer and detergent as revealed by site-directed solid-state 13C NMR.
Related Articles Dynamic pictures of membrane proteins in two-dimensional crystal, lipid bilayer and detergent as revealed by site-directed solid-state 13C NMR.
Chem Phys Lipids. 2004 Nov;132(1):101-12
Authors: Saitô H
We have compared site-directed 13C solid-state NMR spectra of Ala- and/or Val-labeled membrane proteins, including bacteriorhodopsin (bR), pharaonis phoborhodopin (ppR), its cognate...
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11-24-2010 10:03 PM
[NMR paper] Investigating structural changes in the lipid bilayer upon insertion of the transmemb
Investigating structural changes in the lipid bilayer upon insertion of the transmembrane domain of the membrane-bound protein phospholamban utilizing 31P and 2H solid-state NMR spectroscopy.
Related Articles Investigating structural changes in the lipid bilayer upon insertion of the transmembrane domain of the membrane-bound protein phospholamban utilizing 31P and 2H solid-state NMR spectroscopy.
Biophys J. 2004 Mar;86(3):1564-73
Authors: Dave PC, Tiburu EK, Damodaran K, Lorigan GA
Phospholamban (PLB) is a 52-amino acid integral membrane...
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11-24-2010 09:25 PM
[NMR paper] Structure of gramicidin a in a lipid bilayer environment determined using molecular d
Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data.
Related Articles Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data.
J Am Chem Soc. 2003 Aug 13;125(32):9868-77
Authors: Allen TW, Andersen OS, Roux B
Two different high-resolution structures recently have been proposed for the membrane-spanning gramicidin A channel: one based on solid-state NMR experiments in oriented phospholipid...
Membrane-Dependent Modulation of the mTOR ActivatorRheb: NMR Observations of a GTPase Tethered to a Lipid-Bilayer Nanodisc
Linear Mode
