Titanium(IV) complexes of diaminobis(phenolato)-bis(alkoxo) ligands are promising anticancer drugs, showing marked in-vivo efficacy with no toxic side-effects in mice, hence, it is of interest to elucidate their mechanism of action. Herein, we employed a fluoro-substituted derivative, FenolaTi, for mechanistic analysis of the active species and its cellular target by quantitative ^(19)F NMR detection to reveal its biodistribution and reactivity in extracellular and intracellular matrices. Upon...
[NMR paper] A Comparative Study of Secondary Structure and Interactions of the R5 Peptide in Silicon Oxide and Titanium Oxide Co-precipitates using Solid-state NMR Spectroscopy.
A Comparative Study of Secondary Structure and Interactions of the R5 Peptide in Silicon Oxide and Titanium Oxide Co-precipitates using Solid-state NMR Spectroscopy.
Related Articles A Comparative Study of Secondary Structure and Interactions of the R5 Peptide in Silicon Oxide and Titanium Oxide Co-precipitates using Solid-state NMR Spectroscopy.
Langmuir. 2017 Sep 12;:
Authors: Buckle EL, Roehrich A, Vandermoon B, Drobny GP
Abstract
A biomimetic, peptide-mediated approach to inorganic nanostructure formation is of great interest...
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09-13-2017 08:48 PM
Detection and Differentiation of Neutral Organic Compounds by 19F NMR with a Tungsten Calix[4]arene Imido Complex
Detection and Differentiation of Neutral Organic Compounds by 19F NMR with a Tungsten Calixarene Imido Complex
Yanchuan Zhao and Timothy M. Swager
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja4106804/aop/images/medium/ja-2013-106804_0001.gif
Journal of the American Chemical Society
DOI: 10.1021/ja4106804
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/nCRZ8NkiIfo
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12-04-2013 03:11 AM
[NMR paper] Tracing Metabolite Footsteps of Escherichia coli Along the Time Course of Recombinant Protein Expression by Two-Dimensional NMR Spectroscopy.
Tracing Metabolite Footsteps of Escherichia coli Along the Time Course of Recombinant Protein Expression by Two-Dimensional NMR Spectroscopy.
Related Articles Tracing Metabolite Footsteps of Escherichia coli Along the Time Course of Recombinant Protein Expression by Two-Dimensional NMR Spectroscopy.
Bull Korean Chem Soc. 2012 Dec 20;33(12):4041-4046
Authors: Chae YK, Kim SH, Ellinger JJ, Markley JL
Abstract
The recombinant expression of proteins has been the method of choice to meet the demands from proteomics and structural genomics...
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06-26-2013 09:39 AM
Mouthwash: An anticancer solution
Mouthwash: An anticancer solution
http://www.spectroscopynow.com/common/images/thumbnails/13da7b35fbf.jpgThe active ingredients in some commercially available mouthwash solution, the bisbiguanide oral disinfectants chlorhexidine (Chlorhexamed, Chlorhexal, Periogard, Corsodyl, and Chlorohex) and alexidine (Esemdent) have been in widespread use for many years. Now, 1H,15N-HSQC NMR spectroscopy has been used in studies to investigate the structural changes these compounds can induce that lead to apoptosis in oral cancer cells.
Read the rest at Spectroscopynow.com
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04-01-2013 03:38 AM
Characterization of Sarcoplasmic Reticulum Ca(2+) ATPase Nucleotide Binding Domain Mutants using NMR spectroscopy.
Characterization of Sarcoplasmic Reticulum Ca(2+) ATPase Nucleotide Binding Domain Mutants using NMR spectroscopy.
Characterization of Sarcoplasmic Reticulum Ca(2+) ATPase Nucleotide Binding Domain Mutants using NMR spectroscopy.
Biochem Biophys Res Commun. 2010 Dec 24;
Authors: Myint W, Gong Q, Ahn J, Ishima R
Sarcoplasmic reticulum Ca(2+) ATPase (SERCA) is essential for muscle function by transporting Ca(2+) from the cytosol into the sarcoplasmic reticulum through ATP hydrolysis. In this report, the effects of substitution mutations on the...
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12-29-2010 04:04 PM
[NMR paper] Detection of very weak side chain-main chain hydrogen bonding interactions in medium-
Detection of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled proteins by sensitivity-enhanced NMR spectroscopy.
Related Articles Detection of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled proteins by sensitivity-enhanced NMR spectroscopy.
J Biomol NMR. 2000 May;17(1):79-82
Authors: Liu A, Hu W, Majumdar A, Rosen MK, Patel DJ
We describe the direct observation of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled...