Macromolecular NMR spectroscopy for the non-spectroscopist.
FEBS J. 2011 Mar;278(5):687-703
Authors: Kwan AH, Mobli M, Gooley PR, King GF, Mackay JP
NMR spectroscopy is a powerful tool for studying the structure, function and dynamics of biological macromolecules. However, non-spectroscopists often find NMR theory daunting and data interpretation nontrivial. As the first of two back-to-back reviews on NMR spectroscopy aimed at non-spectroscopists, the present review first provides an introduction to the basics of macromolecular NMR spectroscopy, including a discussion of typical sample requirements and what information can be obtained from simple NMR experiments. We then review the use of NMR spectroscopy for determining the 3D structures of macromolecules and examine how to judge the quality of NMR-derived structures.
Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination.
Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination.
Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination.
FEBS J. 2011 Jan 7;
Authors: Bieri M, Kwan AH, Mobli M, King GF, Mackay JP, Gooley PR
A strength of NMR spectroscopy is its ability to monitor, on an atomic level, molecular changes and interactions. In this article, which is intended for non-spectroscopists, we describe major uses of NMR in protein science beyond...
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01-11-2011 11:27 PM
Positions in Biomolecular NMR Spectroscopy:senior NMR spectroscopist, postdoctoral as
Positions in Biomolecular NMR Spectroscopy:senior NMR spectroscopist, postdoctoral associate, techni - CARIM school for Cardiovascular Diseases - Maastricht, Netherlands
Positions in Biomolecular NMR Spectroscopy at Maastricht
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The Maastricht University Medical Center and the Faculty of Health, Medicine and Life Sciences (FHML) seek to fill several positions for the newly established center for NMR Structural Biology within the CARIM School for Cardiovascular Diseases and the Maastricht-Centre...
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09-21-2010 06:43 PM
Macromolecular NMR Spectroscopist
Macromolecular NMR Spectroscopist
The Structural Biophysics Laboratory, National Cancer Institute is seeking the support of a Macromolecular NMR spectroscopist who will work with and support the PIs in the Structural Biophysics Laboratory (SBL) For info on the SBL visit: http://go.cancer.gov/sbljobs]. The position will be hired by the SAIC-Frederick and dedicated to the SBL.
The Scientist II will work with and support principal investigators in the Structural Biophysics Laboratory (SBL) in the determination of biological macromolecular structures using high-field NMR (500-850 MHz...
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08-21-2010 05:17 AM
postdoctoral position in macromolecular NMR
postdoctoral position in macromolecular NMR
There is an opening for a postdoctoral position in macromolecular NMR
and structural biology at the Structural Biophysics Laboratory, National
Cancer Institute, Frederick, MD.
A highly motivated individual is sought to conduct studies in NMR, dynamics,
and integrated structural and functional understanding of proteins and complexes
in the ubiquitination pathway. For an example of the type of work please see
Mol. Cell 34(6):674 . Individuals interested in spectroscopy, new methods, and/or
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08-21-2010 05:14 AM
Macromolecular NMR Spectroscopist
Macromolecular NMR Spectroscopist
The Structural Biophysics Laboratory, National Cancer Institute is seeking the support of a Macromolecular NMR spectroscopist who will work with and support the PIs in the Structural Biophysics Laboratory (SBL) For info on the SBL visit: http://go.cancer.gov/sbljobs]. The position will be hired by the SAIC-Frederick and dedicated to the SBL.
The Scientist II will work with and support principal investigators in the Structural Biophysics Laboratory (SBL) in the determination of biological macromolecular structures using high-field NMR (500-850 MHz...